INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
| Draft as of 2024-03-19 |
Definitions for the ColorectalTumorProfileResultLogicalModel logical model.
Guidance on how to interpret the contents of this table can be found here
| 0. ColorectalTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Colorectal cancer |
| Short | Tumor profile result Colorectal |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. ColorectalTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. ColorectalTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. ColorectalTumorProfileResultLogicalModel.mmr | |
| Definition | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Short | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. ColorectalTumorProfileResultLogicalModel.msi | |
| Definition | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Short | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. ColorectalTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Short | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. ColorectalTumorProfileResultLogicalModel.tgfbr | |
| Definition | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Short | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. ColorectalTumorProfileResultLogicalModel.Loh18q | |
| Definition | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. ColorectalTumorProfileResultLogicalModel.tp53 | |
| Definition | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. ColorectalTumorProfileResultLogicalModel.apc | |
| Definition | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Short | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. ColorectalTumorProfileResultLogicalModel.kRas | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
Guidance on how to interpret the contents of this table can be found here
| 0. ColorectalTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Colorectal cancer |
| Short | Tumor profile result Colorectal |
| Control | 0..* |
| Is Modifier | false |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. ColorectalTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. ColorectalTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. ColorectalTumorProfileResultLogicalModel.mmr | |
| Definition | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Short | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. ColorectalTumorProfileResultLogicalModel.msi | |
| Definition | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Short | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. ColorectalTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Short | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. ColorectalTumorProfileResultLogicalModel.tgfbr | |
| Definition | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Short | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. ColorectalTumorProfileResultLogicalModel.Loh18q | |
| Definition | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. ColorectalTumorProfileResultLogicalModel.tp53 | |
| Definition | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. ColorectalTumorProfileResultLogicalModel.apc | |
| Definition | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Short | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. ColorectalTumorProfileResultLogicalModel.kRas | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
Guidance on how to interpret the contents of this table can be found here
| 0. ColorectalTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Colorectal cancer |
| Short | Tumor profile result Colorectal |
| Control | 0..* |
| Is Modifier | false |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. ColorectalTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. ColorectalTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. ColorectalTumorProfileResultLogicalModel.mmr | |
| Definition | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Short | DNA mismatch repair protein Msh3 [Presence] in Cancer specimen by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. ColorectalTumorProfileResultLogicalModel.msi | |
| Definition | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Short | Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. ColorectalTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Short | PIK3CA gene [VCF] in Cancer specimen by Sequencing |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. ColorectalTumorProfileResultLogicalModel.tgfbr | |
| Definition | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Short | TGFBR1 gene+TGFBR2 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. ColorectalTumorProfileResultLogicalModel.Loh18q | |
| Definition | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | 18q chromosome deletion [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. ColorectalTumorProfileResultLogicalModel.tp53 | |
| Definition | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | TP53 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. ColorectalTumorProfileResultLogicalModel.apc | |
| Definition | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Short | GSTP1 gene+APC gene methylation [Presence] in Tissue by Molecular genetics method |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. ColorectalTumorProfileResultLogicalModel.kRas | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
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