Bundle Breast-Cancer-Message-Bundle-Example of type transaction

Entry 1

Request:

POST MessageHeader

Resource MessageHeader:

Generated Narrative: MessageHeader

Resource MessageHeader "breastmessageheader"

event: Malignant neoplasm of breast (disorder) (Details: http://snomed.org code 254837009 = '254837009', stated as 'Malignant neoplasm of breast (disorder)')

Destinations

-	Name	Endpoint
*	example	https://exemple.com/services?wsdl

sender: See above (Organization/breastorganization01)

Sources

-	Name	Contact	Endpoint
*	example	example@example.en	https://example.en/origin

focus: See above (Patient/breastpatient01)

Entry 2

Request:

POST Organization

Resource Organization:

Generated Narrative: Organization

Resource Organization "breastorganization01"

Profile: Organization for Breast, Colorectal, Lung and Prostate cancer

identifier: AUTH/?ngen-9?

name: Aristotle university of Thessaloniki

Entry 3

Request:

POST Medication

Resource Medication:

Generated Narrative: Medication

Resource Medication "breastmedication01"

code: Medication therapy (snomed.org#373873005 "Pharmaceutical / biologic product (product)")

status: ACTIVE

Entry 4

Request:

POST Patient

Resource Patient:

Female, DoB: ( Pseudo-anonimized Identifier: 004-000001)

Entry 5

Request:

POST Condition

Resource Condition:

Generated Narrative: Condition

Resource Condition "breastcondition01"

Profile: Condition for Breast, Colorectal, Lung and Prostate cancer

code: N39.8 (SNOMED CT#417662000 "History of clinical finding in subject (situation)")

subject: See above (Patient/breastpatient01)

Entry 6

Request:

POST Condition

Resource Condition:

Generated Narrative: Condition

Resource Condition "breastcondition02"

Profile: Condition for Breast, Colorectal, Lung and Prostate cancer

code: Symptoms and signs observed (record artifact) (snomed.org#63671000122101)

subject: See above (Patient/breastpatient01)

evidence

Entry 7

Request:

POST Condition

Resource Condition:

Generated Narrative: Condition

Resource Condition "breastcondition03"

Profile: Condition for Breast, Colorectal, Lung and Prostate cancer

code: Clinical finding (finding) (SNOMED CT#404684003)

subject: See above (Patient/breastpatient01)

note: Dysuria

Entry 8

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation01"

Profile: Observation for Breast cancer

status: FINAL

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

note: Observation note

component

code: Number of births at term (observable entity) (snomed.org#440425000)

value: 2

component

code: Menopause, function (observable entity) (snomed.org#161712005)

value: Pre (Pre_post_menopause_Breast#0)

component

code: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| (snomed.org#275937001:408732007=66839005)

value: true

component

code: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| (snomed.org#275937001:408732007=72705000)

value: true

component

code: Carcinoembryonic Ag [Mass/volume] in Serum or Plasma (LOINC#2039-6)

value: 11.9 nanogram per milliliter (Details: UCUM code ng/mL = 'ng/mL')

component

code: Cancer Ag 15-3 [Units/volume] in Serum or Plasma (snomed.org#6875-9)

value: 37 enzyme unit per millilitre (Details: UCUM code U/mL = 'U/mL')

Entry 9

Request:

POST DiagnosticReport

Resource DiagnosticReport:

Malignant neoplasm of breast (disorder)

Subject

Not done yet

Report Details

Code	Value	Note
Malignant neoplasm of breast (disorder)		Observation note

Entry 10

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation02"

Profile: Observation for Breast cancer

status: FINAL

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

bodySite: Bone (Distant_metastasis_location_Breast#1)

component

code: Laboratory procedure performed (situation) (snomed.org#165331007)

value: true

component

code: Mammography.dcm-path (snomed.org#71651007 "Mammography (procedure)")

value: true

component

code: Annotated Mammography.dcm-path (snomed.org#397137005 "Mammography assessment finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Ultrasound.dcm-path (snomed.org#16310003 "Diagnostic ultrasonography (procedure)")

value: true

component

code: Annotated Ultrasound.dcm-path (snomed.org#370380004 "Ultrasound scan finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Primary tumor size (observable entity) (snomed.org#399734001)

value: 4.8 centimetre (Details: UCUM code cm = 'cm')

component

code: Laterality (attribute) (snomed.org#272741003)

value: Right breast (Breast_laterality#0)

component

code: Radiographic lesion shape finding (finding) (snomed.org#129732008)

value: Oval (Mass_Shape_Breast#1)

component

code: Radiographic lesion margin characteristics (finding) (snomed.org#129737002)

value: Angular (Mass_Margin_Breast#2)

component

code: Mammography reference location (finding) (snomed.org#129771006)

value: Parallel (Mass_orientation_Breast#1)

component

code: Acoustic feature of mass (observable entity) (snomed.org#420415002)

value: Anechoic (Mass_echo_pattern_Breast#1)

component

code: Finding of change compared to previous radiologic examination (finding) (snomed.org#442301001)

value: Shadowing (Posterior_features_Breast#3)

component

code: Tumor calcification (finding) (snomed.org#409769002)

value: In mass (Calcifications_baseline_Breast#1)

component

code: Associated finding (attribute) (snomed.org#246090004)

value: Skin thickness (Associated_Features_Breast#1)

component

code: Mammographic breast composition finding (finding) (snomed.org#129715009)

value: Fatty (Breast_composition#1)

component

code: Mammographic architectural distortion of breast (finding) (snomed.org#129792006)

value: Minimal (Parenchymal_enhancement_level_Breast#1)

component

code: Tumor configuration (observable entity) (snomed.org#371500007)

value: Symmetric (Parenchymal_enhancement_symmetry_Breast#1)

component

code: Qualitative distribution of primary malignant neoplasm (observable entity) (snomed.org#1163261007)

value: Unifocal (Presence_of_foci_Breast#1)

component

code: Tumor staging (tumor staging) (snomed.org#254292007)

value: Incomplete need additional imaging evaluation (Breast_BIRADS_classification#BI-RADS 0)

component

code: Tumor staging (tumor staging) (snomed.org#254292007)

value: Negative symmetrical and no masses, architectural distortion, or suspicious calcifications (Breast_BIRADS_classification#BI-RADS 1)

component

code: Primary malignant neoplasm of breast with axillary lymph node invasion (disorder) (snomed.org#1082901000112100)

value: true

component

code: Injury of breast (disorder) (snomed.org#62112002)

value: true

component

code: pM category (observable entity) (snomed.org#371497001)

value: true

component

code: T category (observable entity) (snomed.org#78873005)

value: T0

component

code: N category (observable entity) (snomed.org#277206009)

value: N0

component

code: M category (observable entity) (snomed.org#277208005)

value: M0

Entry 11

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation03"

Profile: Observation for Breast cancer

status: FINAL

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

bodySite: Nipple and Areola (Baseline_location_Breast#AN)

component

code: CT.dcm-path (snomed.org#77477000 "Computed tomography (procedure)")

value: true

component

code: Annotated CT.dcm-path (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: MRI.dcm-path (snomed.org#113091000 "Magnetic resonance imaging (procedure)")

value: true

component

code: Annotated MRI.dcm-path (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: PET/CT.dcm-path (snomed.org#82918005 "Positron emission tomography (procedure)")

value: true

component

code: Annotated PET/CT.dcm-path (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Histopathology Image.dcm-path (snomed.org#252416005 "Histopathology test (procedure)")

value: true

component

code: Annotated Histopathology Image.dcm-path (snomed.org#250537006 "Histopathology finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Xray.dcm-path (snomed.org#363680008 "Radiographic imaging procedure (procedure)")

value: true

component

code: Annotated Xray.dcm-path (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

Entry 12

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure01"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Surgery (snomed.org#129125009 "Procedure with explicit context (situation)")

subject: See above (Patient/breastpatient01)

Entry 13

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation04"

Profile: Observation for Breast cancer

partOf: See above (Procedure/breastprocedure01)

status: FINAL

category: Between 1st and 2nd dose of CT (), Label timepoints ()

code: After 1st Treatment (Label_Timepoints#1)

subject: See above (Patient/breastpatient01)

value: 2

note: Observation note

bodySite: Bone (Distant_metastasis_location_Breast#1)

component

code: Mammography.dcm-path (snomed.org#71651007 "Mammography (procedure)")

value: true

component

code: Annotated Mammography.dcm-path (snomed.org#397137005 "Mammography assessment finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Ultrasound.dcm-path (snomed.org#16310003 "Diagnostic ultrasonography (procedure)")

value: true

component

code: Annotated Ultrasound.dcm-path (snomed.org#370380004 "Ultrasound scan finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: CT.dcm-path (snomed.org#77477000 "Computed tomography (procedure)")

value: true

component

code: Annotated CT.dcm-path (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: MRI.dcm-path (snomed.org#113091000 "Magnetic resonance imaging (procedure)")

value: true

component

code: Annotated MRI.dcm-path (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: PET/CT.dcm-path (snomed.org#82918005 "Positron emission tomography (procedure)")

value: true

component

code: Annotated PET/CT.dcm-path (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Histopathology Image.dcm-path (snomed.org#252416005 "Histopathology test (procedure)")

value: true

component

code: Annotated Histopathology Image.dcm-path (snomed.org#250537006 "Histopathology finding (finding)")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Xray.dcm-path (snomed.org#363680008 "Radiographic imaging procedure (procedure)")

value: true

component

code: Annotated Xray.dcm-path (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")

value: Positive annotation (Annotated_Dicom_files_Breast#1)

component

code: Laboratory procedure performed (situation) (snomed.org#165331007)

value: true

component

code: Response to treatment (situation) (snomed.org#182985004)

value: CR (Response_to_treatment_Breast#1)

component

code: T category (observable entity) (snomed.org#78873005)

value: T0

component

code: N category (observable entity) (snomed.org#277206009)

value: N0

component

code: M category (observable entity) (snomed.org#277208005)

value: M0

component

code: Tumor staging (tumor staging) (snomed.org#254292007)

value: Incomplete need additional imaging evaluation (Breast_BIRADS_classification#BI-RADS 0)

component

code: Tumor staging (tumor staging) (snomed.org#254292007)

value: Negative symmetrical and no masses, architectural distortion, or suspicious calcifications (Breast_BIRADS_classification#BI-RADS 1)

component

code: Length dimension of neoplasm (observable entity) (snomed.org#263605001)

value: 4.8 centimetre (Details: UCUM code cm = 'cm')

component

code: Primary malignant neoplasm of breast with axillary lymph node invasion (disorder) (snomed.org#1082901000112100)

value: true

component

code: |Lesion observable (observable entity)|:|Relative to part of (attribute)|=|Breast structure (body structure)| (snomed.org#364636000:719715003=76752008)

value: true

component

code: pM category (observable entity) (snomed.org#371497001)

value: true

component

code: |Follow-up status (finding)|:|After (attribute)=|Biopsy (procedure)| (snomed.org#308273005:255234002=86273004)

value: true

component

code: |Follow-up status (finding)|:|After (attribute)|=|Surgical procedure (procedure)| (snomed.org#308273005:255234002=387713003)

value: true

component

code: Tumor progression (finding) (snomed.org#419835002)

value: true

component

code: Radiographic lesion shape finding (finding) (snomed.org#129732008)

value: Oval (Mass_Shape_Breast#1)

component

code: Radiographic lesion margin characteristics (finding) (snomed.org#129737002)

value: Angular (Mass_Margin_Breast#2)

component

code: Mammography reference location (finding) (snomed.org#129771006)

value: Parallel (Mass_orientation_Breast#1)

component

code: Acoustic feature of mass (observable entity) (snomed.org#420415002)

value: Anechoic (Mass_echo_pattern_Breast#1)

component

code: Finding of change compared to previous radiologic examination (finding) (snomed.org#442301001)

value: Shadowing (Posterior_features_Breast#3)

component

code: Tumor calcification (finding) (snomed.org#409769002)

value: In mass (Calcifications_timepoints_Breast#1)

component

code: Tumor calcification (finding) (snomed.org#246090004)

value: Skin thickness (Associated_Features_Breast#1)

component

code: Mammographic breast composition finding (finding) (snomed.org#129715009)

value: Fatty (Breast_composition#1)

component

code: Mammographic architectural distortion of breast (finding) (snomed.org#129792006)

value: Minimal (Parenchymal_enhancement_level_Breast#1)

component

code: Tumor configuration (observable entity) (snomed.org#371500007)

value: Symmetric (Parenchymal_enhancement_symmetry_Breast#1)

component

code: Qualitative distribution of primary malignant neoplasm (observable entity) (snomed.org#1163261007)

value: Unifocal (Presence_of_foci_Breast#1)

component

code: Treatment changed (situation) (snomed.org#445528004)

value: true

Entry 14

Request:

POST Condition

Resource Condition:

Generated Narrative: Condition

Resource Condition "breastcondition04"

Profile: Condition for Breast, Colorectal, Lung and Prostate cancer

code: Symptoms and signs observed (record artifact) (snomed.org#63671000122101)

subject: See above (Patient/breastpatient01)

evidence

Entry 15

Request:

POST Condition

Resource Condition:

Generated Narrative: Condition

Resource Condition "breastcondition05"

Profile: Condition for Breast, Colorectal, Lung and Prostate cancer

code: Clinical finding (finding) (SNOMED CT#404684003)

subject: See above (Patient/breastpatient01)

note: Dysuria

Entry 16

Request:

POST MedicationAdministration

Resource MedicationAdministration:

Generated Narrative: MedicationAdministration

Resource MedicationAdministration "breastmedicationAdministration01"

status: COMPLETED

subject: See above (Patient/breastpatient01)

Dosages

-	Route	Dose	Rate[x]
*	|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Breast structure (body structure)|, |Units (attribute)|=|Gray (qualifier value)| (snomed.org#371892002:704327008=76752008, 246514001=229029004)	40.4	28 fractions

Entry 17

Request:

POST MedicationAdministration

Resource MedicationAdministration:

Generated Narrative: MedicationAdministration

Resource MedicationAdministration "breastmedicationAdministration02"

status: COMPLETED

category: Boost radiation therapy (procedure) (snomed.org#445232009)

subject: See above (Patient/breastpatient01)

Dosages

-	Route	Dose	Rate[x]
*	|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Tumor bed (morphologic abnormality)|, |Units (attribute)|=|Gray (qualifier value)| (snomed.org#371892002:704327008=1162492000, 246514001=229029004)	50.4	7 fractions

Entry 18

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation05"

Profile: Observation for Breast cancer

partOf:

• See above (MedicationAdministration/breastmedicationAdministration01)
• See above (MedicationAdministration/breastmedicationAdministration02)

status: FINAL

code: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Neo-adjuvant - intent (qualifier value)| (snomed.org#18629005:363703001=373847000)

subject: See above (Patient/breastpatient01)

value: true

Entry 19

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation06"

Profile: Observation for Breast cancer

partOf:

• See above (MedicationAdministration/breastmedicationAdministration01)
• See above (MedicationAdministration/breastmedicationAdministration02)

status: FINAL

code: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Adjuvant - intent (qualifier value)| (snomed.org#18629005:363703001=373846009)

subject: See above (Patient/breastpatient01)

value: true

Entry 20

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation07"

Profile: Observation for Breast cancer

status: FINAL

category: Between 1st and 2nd dose of CT (), Label treatment ()

code: After 1st Treatment-1st FollowUp (Label_Treatment#1)

subject: See above (Patient/breastpatient01)

value: Other treatment details

Components

-	Code	Value[x]
*	Performance measure status (finding) (snomed.org#241000124106)	5

Entry 21

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation08"

Profile: Observation for Breast cancer

status: FINAL

code: Procedure on lymph node (procedure) (snomed.org#118890000)

subject: See above (Patient/breastpatient01)

value: No (Lymph_node_surgery_Breast#0)

Entry 22

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure02"

Profile: Procedure for Breast cancer

partOf: See above (Observation/breastobservation08)

status: COMPLETED

category: Mastectomy (Type_of_Surgery_Breast#2)

code: Surgical procedure (procedure) (snomed.org#387713003)

subject: See above (Patient/breastpatient01)

Entry 23

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure03"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Capecitabine (snomed.org#367336001:370130000=410656007 "|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 24

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure04"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Nitrosoureas (snomed.org#703423002:370130000=410656007 "|Combined chemotherapy and radiation therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 25

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure05"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Tamoxifen (snomed.org#897713009:370130000=410656007 "|Antineoplastic chemoimmunotherapy (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 26

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure06"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Tamoxifen (snomed.org#385798007:370130000=410656007 "|Radiation therapy care (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 27

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure07"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Tamoxifen (snomed.org#169413002:370130000=410656007 "|Hormone therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 28

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure08"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Trastuzumab (snomed.org#6021000124103:370130000=410656007 "|Targeted medication therapy review (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 29

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure09"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Pembrolizumab (snomed.org#76334006:370130000=410656007 "|Immunotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")

subject: See above (Patient/breastpatient01)

Entry 30

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation09"

Profile: Observation for Breast cancer

status: FINAL

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

component

code: HER2 [Presence] in Breast cancer specimen by Immune stain (LOINC#85319-2)

value: true

component

code: Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain (LOINC#85337-4)

value: true

component

code: Progesterone receptor Ag [Presence] in Breast cancer specimen by Immune stain (LOINC#85339-0)

value: true

component

code: Melan-A and Ki67 Ag [Identifier] in Tissue by Immune stain (LOINC#74489-6)

value: 10 % percent (Details: UCUM code % = '%')

component

code: BRCA1 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal (LOINC#21639-0)

value: true

component

code: BRCA1+BRCA2 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal (LOINC#59041-4)

value: true

component

code: Lymphovascular invasion extent in Cancer specimen Qualitative (LOINC#98260-3)

value: true

Entry 31

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation10"

Profile: Observation for Breast cancer

status: FINAL

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

component

code: Sampling - action (qualifier value) (snomed.org#257915005)

value: Light microscopy

component

code: Staining method (procedure) (snomed.org#127790008)

value: Hematoxylin

component

code: Microscopic specimen observation (finding) (snomed.org#395538009)

value: x10

component

code: Biopsy finding (finding) (snomed.org#365855009)

value: example

Entry 32

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure10"

Profile: Procedure for Breast cancer

status: COMPLETED

statusReason: Biopsy label (Label_Biopsy#1 "After 1st Treatment")

category: Between 1st and 2nd dose of CT (Type_of_Biopsy_Breast#1 "FNAC")

code: Biopsy (procedure) (snomed.org#86273004)

subject: See above (Patient/breastpatient01)

Entry 33

Request:

POST Procedure

Resource Procedure:

Generated Narrative: Procedure

Resource Procedure "breastprocedure11"

Profile: Procedure for Breast cancer

status: COMPLETED

code: Surgical procedure (procedure) (snomed.org#387713003)

subject: See above (Patient/breastpatient01)

Entry 34

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation11"

Profile: Observation for Breast cancer

status: FINAL

category: Inflammatory Breast Carcinoma (Breast_Cancer_Type#IBC; Molecular_Subtype_Breast#1 "Luminal A")

code: Malignant neoplasm of breast (disorder) (snomed.org#254837009)

subject: See above (Patient/breastpatient01)

Components

-	Code	Value[x]
*	|Malignant neoplasm of breast (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| (snomed.org#254837009:363714003=443941007)	1

Entry 35

Request:

POST Observation

Resource Observation:

Generated Narrative: Observation

Resource Observation "breastobservation12"

Profile: Observation for Breast cancer

status: FINAL

category: Between 1st and 2nd dose of CT (), Exam label ()

code: After 1st Treatment (Label_Exam#1)

subject: See above (Patient/breastpatient01)

value: 2

component

code: Leukocytes [#/volume] in Stem cell product (LOINC#95218-4)

value: 15.8 per microlitre (Details: UCUM code x10^9/L = 'x10^9/L')

component

code: Hemoglobin [Mass/volume] in Blood (LOINC#718-7)

value: 16.7 gram per decilitre (Details: UCUM code gr/dL = 'gr/dL')

component

code: Hematocrit [Volume Fraction] of Blood (LOINC#20570-8)

value: 47.4 % percent (Details: UCUM code % = '%')

component

code: Platelets [#/volume] in Blood (LOINC#26515-7)

value: 287 per nanolitre (Details: UCUM code x10^3/μL = 'x10^3/μL')

component

code: Glucose [Mass/volume] in Venous blood (LOINC#41652-9)

value: 87 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Insulin [Units/volume] in Serum or Plasma (LOINC#20448-7)

value: 4 milli-international unit per litre (Details: UCUM code mlU/L = 'mlU/L')

component

code: Urea [Mass/volume] in Blood (LOINC#20977-5)

value: 36 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Creatinine [Mass/volume] in Blood (LOINC#38483-4)

value: 0.72 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Urate [Mass/volume] in Blood (LOINC#98981-4)

value: 3.5 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Potassium [Mass/volume] in Blood (LOINC#75940-7)

value: 4.8 millimole per litre (Details: UCUM code mmol/L = 'mmol/L')

component

code: Sodium [Moles/volume] in Blood (LOINC#2947-0)

value: 142 millimole per litre (Details: UCUM code mmol/L = 'mmol/L')

component

code: Calcium [Mass/volume] in Blood (LOINC#49765-1)

value: 9.31 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Cholesterol [Mass/volume] in Serum or Plasma (LOINC#2093-3)

value: 197 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Triglyceride [Mass/volume] in Blood (LOINC#3043-7)

value: 59 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Cholesterol in HDL [Mass/volume] in Serum or Plasma (LOINC#2085-9)

value: 60 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Cholesterol in LDL [Mass/volume] in Serum or Plasma (LOINC#2089-1)

value: 120 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma (LOINC#1920-8)

value: 19 enzyme unit per litre (Details: UCUM code U/L = 'U/L')

component

code: Alanine aminotransferase [Enzymatic activity/volume] in Blood (LOINC#76625-3)

value: 33 enzyme unit per litre (Details: UCUM code U/L = 'U/L')

component

code: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma (LOINC#2324-2)

value: 14 enzyme unit per litre (Details: UCUM code U/L = 'U/L')

component

code: Alkaline phosphatase [Enzymatic activity/volume] in Blood (LOINC#1783-0)

value: 227 enzyme unit per litre (Details: UCUM code U/L = 'U/L')

component

code: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells (LOINC#11053-6)

value: 270 enzyme unit per litre (Details: UCUM code U/L = 'U/L')

component

code: Thyrotropin [Units/volume] in Blood (LOINC#3015-5)

value: 0.73 milli-international unit per litre (Details: UCUM code mlU/L = 'mlU/L')

component

code: Cortisol [Mass/volume] in Serum or Plasma (LOINC#2143-6)

value: 22 gram per decilitre (Details: UCUM code g/dL = 'g/dL')

component

code: C reactive protein [Mass/volume] in Blood by High sensitivity method (LOINC#71426-1)

value: 0.5 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')

component

code: Natriuretic peptide B [Mass/volume] in Blood (LOINC#42637-9)

value: 120 picogram per millilitre (Details: UCUM code pg/mL = 'pg/mL')

component

code: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC (LOINC#17856-6)

value: 5.1 % percent (Details: UCUM code % = '%')

component

code: Albumin/Protein.total in 24 hour Urine by Electrophoresis (LOINC#13986-5)

value: 80 milligram per 24 hour (Details: UCUM code mg/24h = 'mg/24h')

component

code: Creatinine [Mass/volume] in Urine (LOINC#2161-8)

value: 100 milligram per decilitre (Details: UCUM code mg/dL = 'mg/dL')