INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
| Draft as of 2024-03-19 |
Definitions for the LungTumorProfileResultLogicalModel logical model.
Guidance on how to interpret the contents of this table can be found here
| 0. LungTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Lung cancer |
| Short | Tumor profile result Lung |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. LungTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. LungTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. LungTumorProfileResultLogicalModel.pdl1 | |
| Definition | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Short | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. LungTumorProfileResultLogicalModel.kras | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. LungTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. LungTumorProfileResultLogicalModel.erbb2 | |
| Definition | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. LungTumorProfileResultLogicalModel.igf1r | |
| Definition | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Short | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Control | 1..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. LungTumorProfileResultLogicalModel.ros1 | |
| Definition | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Short | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. LungTumorProfileResultLogicalModel.ret | |
| Definition | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. LungTumorProfileResultLogicalModel.met | |
| Definition | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 22. LungTumorProfileResultLogicalModel.her2 | |
| Definition | HER2 Ag [Presence] in Tissue by Immune stain |
| Short | HER2 Ag [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 24. LungTumorProfileResultLogicalModel.egfr | |
| Definition | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | decimal |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 26. LungTumorProfileResultLogicalModel.alk | |
| Definition | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 28. LungTumorProfileResultLogicalModel.braf | |
| Definition | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
Guidance on how to interpret the contents of this table can be found here
| 0. LungTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Lung cancer |
| Short | Tumor profile result Lung |
| Control | 0..* |
| Is Modifier | false |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. LungTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. LungTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. LungTumorProfileResultLogicalModel.pdl1 | |
| Definition | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Short | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. LungTumorProfileResultLogicalModel.kras | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. LungTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. LungTumorProfileResultLogicalModel.erbb2 | |
| Definition | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. LungTumorProfileResultLogicalModel.igf1r | |
| Definition | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Short | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Control | 1..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. LungTumorProfileResultLogicalModel.ros1 | |
| Definition | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Short | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. LungTumorProfileResultLogicalModel.ret | |
| Definition | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. LungTumorProfileResultLogicalModel.met | |
| Definition | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 22. LungTumorProfileResultLogicalModel.her2 | |
| Definition | HER2 Ag [Presence] in Tissue by Immune stain |
| Short | HER2 Ag [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 24. LungTumorProfileResultLogicalModel.egfr | |
| Definition | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | decimal |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 26. LungTumorProfileResultLogicalModel.alk | |
| Definition | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 28. LungTumorProfileResultLogicalModel.braf | |
| Definition | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
Guidance on how to interpret the contents of this table can be found here
| 0. LungTumorProfileResultLogicalModel | |
| Definition | INCISIVE based logical model for the tumor profile result of Lung cancer |
| Short | Tumor profile result Lung |
| Control | 0..* |
| Is Modifier | false |
| Logical Model | Instances of this logical model are not marked to be the target of a Reference |
| 2. LungTumorProfileResultLogicalModel.tumorProfileResultID | |
| Definition | An identifier for the tumor profile result |
| Short | An identifier for the tumor profile result |
| Control | 1..1 |
| Type | Identifier |
| 4. LungTumorProfileResultLogicalModel.patientID | |
| Definition | INCISIVE patient |
| Short | INCISIVE patient |
| Control | 1..1 |
| Type | https://fhir.incisive-project.eu/StructureDefinition/INCISIVEPatientLogicalModel |
| 6. LungTumorProfileResultLogicalModel.pdl1 | |
| Definition | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Short | PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 8. LungTumorProfileResultLogicalModel.kras | |
| Definition | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 10. LungTumorProfileResultLogicalModel.pik3ca | |
| Definition | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 12. LungTumorProfileResultLogicalModel.erbb2 | |
| Definition | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 14. LungTumorProfileResultLogicalModel.igf1r | |
| Definition | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Short | Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain |
| Control | 1..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 16. LungTumorProfileResultLogicalModel.ros1 | |
| Definition | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Short | Chromosome region 6q22 rearrangements in Tissue by FISH |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 18. LungTumorProfileResultLogicalModel.ret | |
| Definition | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 20. LungTumorProfileResultLogicalModel.met | |
| Definition | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 22. LungTumorProfileResultLogicalModel.her2 | |
| Definition | HER2 Ag [Presence] in Tissue by Immune stain |
| Short | HER2 Ag [Presence] in Tissue by Immune stain |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 24. LungTumorProfileResultLogicalModel.egfr | |
| Definition | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Short | EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | decimal |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 26. LungTumorProfileResultLogicalModel.alk | |
| Definition | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
| 28. LungTumorProfileResultLogicalModel.braf | |
| Definition | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Short | BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal |
| Control | 0..1 |
| Type | boolean |
| Primitive Value | This primitive element may be present, or absent, or replaced by an extension |
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