INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
{
"resourceType" : "Bundle",
"id" : "Breast-Cancer-Message-Bundle-Example",
"identifier" : {
"value" : "Breast Cancer INCISIVE"
},
"type" : "transaction",
"timestamp" : "2023-07-21T12:29:17.239+02:00",
"entry" : [
{
"resource" : {
"resourceType" : "MessageHeader",
"id" : "breastmessageheader",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MessageHeader_breastmessageheader\"> </a><p><b>Generated Narrative: MessageHeader</b><a name=\"breastmessageheader\"> </a><a name=\"hcbreastmessageheader\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MessageHeader "breastmessageheader" </p></div><p><b>event</b>: Malignant neoplasm of breast (disorder) (Details: http://snomed.org code 254837009 = '254837009', stated as 'Malignant neoplasm of breast (disorder)')</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"https://exemple.com/services?wsdl\">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_breastorganization01\">See above (Organization/breastorganization01)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"mailto:example@example.en\">example@example.en</a></td><td><a href=\"https://example.en/origin\">https://example.en/origin</a></td></tr></table><p><b>focus</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p></div>"
},
"eventCoding" : {
"system" : "http://snomed.org",
"code" : "254837009",
"display" : "Malignant neoplasm of breast (disorder)"
},
"destination" : [
{
"name" : "example",
"endpoint" : "https://exemple.com/services?wsdl"
}
],
"sender" : {
"reference" : "Organization/breastorganization01",
"type" : "Organization"
},
"source" : {
"name" : "example",
"contact" : {
"system" : "email",
"value" : "example@example.en"
},
"endpoint" : "https://example.en/origin"
},
"focus" : [
{
"reference" : "Patient/breastpatient01",
"type" : "Patient"
}
]
},
"request" : {
"method" : "POST",
"url" : "MessageHeader"
}
},
{
"resource" : {
"resourceType" : "Organization",
"id" : "breastorganization01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_breastorganization01\"> </a><p><b>Generated Narrative: Organization</b><a name=\"breastorganization01\"> </a><a name=\"hcbreastorganization01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "breastorganization01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-OrganizationINCISIVE.html\">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>"
},
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders",
"code" : "001",
"display" : "AUTH"
}
]
}
}
],
"name" : "Aristotle university of Thessaloniki"
},
"request" : {
"method" : "POST",
"url" : "Organization"
}
},
{
"resource" : {
"resourceType" : "Medication",
"id" : "breastmedication01",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_breastmedication01\"> </a><p><b>Generated Narrative: Medication</b><a name=\"breastmedication01\"> </a><a name=\"hcbreastmedication01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "breastmedication01" </p></div><p><b>code</b>: Medication therapy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#373873005 "Pharmaceutical / biologic product (product)")</span></p><p><b>status</b>: active</p></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "373873005",
"display" : "Pharmaceutical / biologic product (product)"
}
],
"text" : "Medication therapy"
},
"status" : "active"
},
"request" : {
"method" : "POST",
"url" : "Medication"
}
},
{
"resource" : {
"resourceType" : "Patient",
"id" : "breastpatient01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_breastpatient01\"> </a><p><b>Generated Narrative: Patient</b><a name=\"breastpatient01\"> </a><a name=\"hcbreastpatient01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient "breastpatient01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PatientINCISIVE.html\">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-EthnicityOfPatient.html\">Ethnicity_of_patient</a>#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>gender</b>: female</p><p><b>managingOrganization</b>: <a href=\"#Organization_breastorganization01\">See above (Organization/breastorganization01)</a></p></div>"
},
"extension" : [
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/CurrentState",
"valueCode" : "0"
},
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/Ethnicity",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/EthnicityOfPatient",
"code" : "1",
"display" : "White"
}
]
}
}
],
"identifier" : [
{
"type" : {
"text" : "Pseudo-anonimized Identifier"
},
"value" : "004-000001"
}
],
"gender" : "female",
"managingOrganization" : {
"reference" : "Organization/breastorganization01"
}
},
"request" : {
"method" : "POST",
"url" : "Patient"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "breastcondition01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_breastcondition01\"> </a><p><b>Generated Narrative: Condition</b><a name=\"breastcondition01\"> </a><a name=\"hcbreastcondition01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "breastcondition01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: N39.8 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#417662000 "History of clinical finding in subject (situation)")</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "417662000",
"display" : "History of clinical finding in subject (situation)"
}
],
"text" : "N39.8"
},
"subject" : {
"reference" : "Patient/breastpatient01"
}
},
"request" : {
"method" : "POST",
"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "breastcondition02",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_breastcondition02\"> </a><p><b>Generated Narrative: Condition</b><a name=\"breastcondition02\"> </a><a name=\"hcbreastcondition02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "breastcondition02" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Symptoms and signs observed (record artifact) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#63671000122101)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><h3>Evidences</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Nothing <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastSymptomsGeneralInfo.html\">Symptoms_General_Info_Breast</a>#1)</span></td></tr></table></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "63671000122101",
"display" : "Symptoms and signs observed (record artifact)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01"
},
"evidence" : [
{
"code" : [
{
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastSymptomsGeneralInfo",
"code" : "1",
"display" : "Nothing"
}
]
}
]
}
]
},
"request" : {
"method" : "POST",
"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "breastcondition03",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_breastcondition03\"> </a><p><b>Generated Narrative: Condition</b><a name=\"breastcondition03\"> </a><a name=\"hcbreastcondition03\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "breastcondition03" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Clinical finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#404684003)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Dysuria</p></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "404684003",
"display" : "Clinical finding (finding)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01"
},
"note" : [
{
"text" : "Dysuria"
}
]
},
"request" : {
"method" : "POST",
"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation01\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation01\"> </a><a name=\"hcbreastobservation01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Observation note</p><blockquote><p><b>component</b></p><p><b>code</b>: Number of births at term (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#440425000)</span></p><p><b>value</b>: 2</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Menopause, function (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#161712005)</span></p><p><b>value</b>: Pre <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastPrePostMenopause.html\">Pre_post_menopause_Breast</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Carcinoembryonic Ag [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2039-6)</span></p><p><b>value</b>: 11.9 nanogram per milliliter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code ng/mL = 'ng/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cancer Ag 15-3 [Units/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#6875-9)</span></p><p><b>value</b>: 37 enzyme unit per millilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/mL = 'U/mL')</span></p></blockquote></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "254837009",
"display" : "Malignant neoplasm of breast (disorder)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"note" : [
{
"text" : "Observation note"
}
],
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "440425000",
"display" : "Number of births at term (observable entity)"
}
]
},
"valueInteger" : 2
},
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "161712005",
"display" : "Menopause, function (observable entity)"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastPrePostMenopause",
"code" : "0",
"display" : "Pre"
}
]
}
},
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "275937001:408732007=66839005",
"display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"
}
]
},
"valueBoolean" : true
},
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "275937001:408732007=72705000",
"display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"
}
]
},
"valueBoolean" : true
},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "2039-6",
"display" : "Carcinoembryonic Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity" : {
"value" : 11.9,
"unit" : "nanogram per milliliter",
"system" : "http://unitsofmeasure.org",
"code" : "ng/mL"
}
},
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "6875-9",
"display" : "Cancer Ag 15-3 [Units/volume] in Serum or Plasma"
}
]
},
"valueQuantity" : {
"value" : 37,
"unit" : "enzyme unit per millilitre",
"system" : "http://unitsofmeasure.org",
"code" : "U/mL"
}
}
]
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "DiagnosticReport",
"id" : "breastdiagnosticReport01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_breastdiagnosticReport01\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"breastdiagnosticReport01\"> </a><a name=\"hcbreastdiagnosticReport01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport "breastdiagnosticReport01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DiagnosticReportINCISIVE.html\">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>result</b>: <a href=\"#Observation_breastobservation01\">See above (Observation/breastobservation01)</a></p></div>"
},
"extension" : [
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis",
"valueAge" : {
"value" : 56
}
}
],
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "254837009",
"display" : "Malignant neoplasm of breast (disorder)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01"
},
"result" : [
{
"reference" : "Observation/breastobservation01"
}
]
},
"request" : {
"method" : "POST",
"url" : "DiagnosticReport"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation02",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation02\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation02\"> </a><a name=\"hcbreastobservation02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation02" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>bodySite</b>: Bone <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastDistantMetastasisLocation.html\">Distant_metastasis_location_Breast</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style=\"background: LightGoldenRodYellow; 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{
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"code" : "445528004",
"display" : "Treatment changed (situation)"
}
]
},
"valueBoolean" : true
}
]
},
"request" : {
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"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "breastcondition04",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_breastcondition04\"> </a><p><b>Generated Narrative: Condition</b><a name=\"breastcondition04\"> </a><a name=\"hcbreastcondition04\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "breastcondition04" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Symptoms and signs observed (record artifact) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#63671000122101)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><h3>Evidences</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Breast pain <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastSymptomsTimepoints.html\">Symptoms_Timepoints_Breast</a>#1)</span></td></tr></table></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "63671000122101",
"display" : "Symptoms and signs observed (record artifact)"
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]
},
"subject" : {
"reference" : "Patient/breastpatient01"
},
"evidence" : [
{
"code" : [
{
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastSymptomsTimepoints",
"code" : "1",
"display" : "Breast pain"
}
]
}
]
}
]
},
"request" : {
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"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "breastcondition05",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_breastcondition05\"> </a><p><b>Generated Narrative: Condition</b><a name=\"breastcondition05\"> </a><a name=\"hcbreastcondition05\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "breastcondition05" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Clinical finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#404684003)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Dysuria</p></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "404684003",
"display" : "Clinical finding (finding)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01"
},
"note" : [
{
"text" : "Dysuria"
}
]
},
"request" : {
"method" : "POST",
"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "MedicationAdministration",
"id" : "breastmedicationAdministration01",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationAdministration_breastmedicationAdministration01\"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name=\"breastmedicationAdministration01\"> </a><a name=\"hcbreastmedicationAdministration01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration "breastmedicationAdministration01" </p></div><p><b>status</b>: completed</p><p><b>medication</b>: <a href=\"#Medication_breastmedication01\">See above (Medication/breastmedication01)</a></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>effective</b>: 2023-07-21 17:07:54+0000</p><h3>Dosages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Route</b></td><td><b>Dose</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Breast structure (body structure)|, |Units (attribute)|=|Gray (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#371892002:704327008=76752008, 246514001=229029004)</span></td><td>40.4</td><td>28 fractions</td></tr></table></div>"
},
"status" : "completed",
"medicationReference" : {
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"type" : "Medication"
},
"subject" : {
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"type" : "Patient"
},
"effectiveDateTime" : "2023-07-21T17:07:54+00:00",
"dosage" : {
"route" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "371892002:704327008=76752008, 246514001=229029004",
"display" : "|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Breast structure (body structure)|, |Units (attribute)|=|Gray (qualifier value)|"
}
]
},
"dose" : {
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},
"rateQuantity" : {
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"unit" : "fractions"
}
}
},
"request" : {
"method" : "POST",
"url" : "MedicationAdministration"
}
},
{
"resource" : {
"resourceType" : "MedicationAdministration",
"id" : "breastmedicationAdministration02",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicationAdministration_breastmedicationAdministration02\"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name=\"breastmedicationAdministration02\"> </a><a name=\"hcbreastmedicationAdministration02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationAdministration "breastmedicationAdministration02" </p></div><p><b>status</b>: completed</p><p><b>category</b>: Boost radiation therapy (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#445232009)</span></p><p><b>medication</b>: <a href=\"#Medication_breastmedication01\">See above (Medication/breastmedication01)</a></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>effective</b>: 2023-07-21 17:07:54+0000</p><h3>Dosages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Route</b></td><td><b>Dose</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Tumor bed (morphologic abnormality)|, |Units (attribute)|=|Gray (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#371892002:704327008=1162492000, 246514001=229029004)</span></td><td>50.4</td><td>7 fractions</td></tr></table></div>"
},
"status" : "completed",
"category" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "445232009",
"display" : "Boost radiation therapy (procedure)"
}
]
},
"medicationReference" : {
"reference" : "Medication/breastmedication01",
"type" : "Medication"
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"effectiveDateTime" : "2023-07-21T17:07:54+00:00",
"dosage" : {
"route" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "371892002:704327008=1162492000, 246514001=229029004",
"display" : "|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Tumor bed (morphologic abnormality)|, |Units (attribute)|=|Gray (qualifier value)|"
}
]
},
"dose" : {
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},
"rateQuantity" : {
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"unit" : "fractions"
}
}
},
"request" : {
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"url" : "MedicationAdministration"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation05",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation05\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation05\"> </a><a name=\"hcbreastobservation05\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation05" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>partOf</b>: </p><ul><li><a href=\"#MedicationAdministration_breastmedicationAdministration01\">See above (MedicationAdministration/breastmedicationAdministration01)</a></li><li><a href=\"#MedicationAdministration_breastmedicationAdministration02\">See above (MedicationAdministration/breastmedicationAdministration02)</a></li></ul><p><b>status</b>: final</p><p><b>code</b>: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Neo-adjuvant - intent (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#18629005:363703001=373847000)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>value</b>: true</p></div>"
},
"partOf" : [
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},
{
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}
],
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"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "18629005:363703001=373847000",
"display" : "|Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Neo-adjuvant - intent (qualifier value)|"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"valueBoolean" : true
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation06",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation06\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation06\"> </a><a name=\"hcbreastobservation06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation06" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>partOf</b>: </p><ul><li><a href=\"#MedicationAdministration_breastmedicationAdministration01\">See above (MedicationAdministration/breastmedicationAdministration01)</a></li><li><a href=\"#MedicationAdministration_breastmedicationAdministration02\">See above (MedicationAdministration/breastmedicationAdministration02)</a></li></ul><p><b>status</b>: final</p><p><b>code</b>: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Adjuvant - intent (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#18629005:363703001=373846009)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>value</b>: true</p></div>"
},
"partOf" : [
{
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},
{
"reference" : "MedicationAdministration/breastmedicationAdministration02"
}
],
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "18629005:363703001=373846009",
"display" : "|Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Adjuvant - intent (qualifier value)|"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"valueBoolean" : true
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation07",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation07\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation07\"> </a><a name=\"hcbreastobservation07\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation07" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span>, Label treatment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: After 1st Treatment-1st FollowUp <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelTreatment.html\">Label_Treatment</a>#1)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>value</b>: Other treatment details</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Performance measure status (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#241000124106)</span></td><td>5</td></tr></table></div>"
},
"status" : "final",
"category" : [
{
"text" : "Between 1st and 2nd dose of CT"
},
{
"text" : "Label treatment"
}
],
"code" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/LabelTreatment",
"code" : "1",
"display" : "After 1st Treatment-1st FollowUp"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"valueString" : "Other treatment details",
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "241000124106",
"display" : "Performance measure status (finding)"
}
]
},
"valueInteger" : 5
}
]
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation08",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation08\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation08\"> </a><a name=\"hcbreastobservation08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation08" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Procedure on lymph node (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#118890000)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>value</b>: No <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastLymphNodeSurgery.html\">Lymph_node_surgery_Breast</a>#0)</span></p></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "118890000",
"display" : "Procedure on lymph node (procedure)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastLymphNodeSurgery",
"code" : "0",
"display" : "No"
}
]
}
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Procedure",
"id" : "breastprocedure02",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_breastprocedure02\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"breastprocedure02\"> </a><a name=\"hcbreastprocedure02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure "breastprocedure02" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForBreast.html\">Procedure for Breast cancer</a></p></div><p><b>partOf</b>: <a href=\"#Observation_breastobservation08\">See above (Observation/breastobservation08)</a></p><p><b>status</b>: completed</p><p><b>category</b>: Mastectomy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastTypeOfSurgery.html\">Type_of_Surgery_Breast</a>#2)</span></p><p><b>code</b>: Surgical procedure (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>"
},
"partOf" : [
{
"reference" : "Observation/breastobservation08"
}
],
"status" : "completed",
"category" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastTypeOfSurgery",
"code" : "2",
"display" : "Mastectomy"
}
]
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "387713003",
"display" : "Surgical procedure (procedure)"
}
]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"performedString" : "2"
},
"request" : {
"method" : "POST",
"url" : "Procedure"
}
},
{
"resource" : {
"resourceType" : "Procedure",
"id" : "breastprocedure03",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_breastprocedure03\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"breastprocedure03\"> </a><a name=\"hcbreastprocedure03\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure "breastprocedure03" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForBreast.html\">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Capecitabine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#367336001:370130000=410656007 "|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>"
},
"status" : "completed",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "367336001:370130000=410656007",
"display" : "|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"
}
],
"text" : "Capecitabine"
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"performedString" : "2"
},
"request" : {
"method" : "POST",
"url" : "Procedure"
}
},
{
"resource" : {
"resourceType" : "Procedure",
"id" : "breastprocedure04",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"
]
},
"text" : {
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"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_breastprocedure11\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"breastprocedure11\"> </a><a name=\"hcbreastprocedure11\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure "breastprocedure11" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForBreast.html\">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgical procedure (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>"
},
"status" : "completed",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "387713003",
"display" : "Surgical procedure (procedure)"
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]
},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
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"performedString" : "2"
},
"request" : {
"method" : "POST",
"url" : "Procedure"
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},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation11",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation11\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation11\"> </a><a name=\"hcbreastobservation11\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation11" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Inflammatory Breast Carcinoma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-BreastCancerType.html\">Breast_Cancer_Type</a>#IBC; <a href=\"CodeSystem-BreastMolecularSubtype.html\">Molecular_Subtype_Breast</a>#1 "Luminal A")</span></p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>|Malignant neoplasm of breast (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#254837009:363714003=443941007)</span></td><td>1</td></tr></table></div>"
},
"status" : "final",
"category" : [
{
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastCancerType",
"code" : "IBC",
"display" : "Inflammatory Breast Carcinoma"
},
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/BreastMolecularSubtype",
"code" : "1",
"display" : "Luminal A"
}
]
}
],
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "254837009",
"display" : "Malignant neoplasm of breast (disorder)"
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},
"subject" : {
"reference" : "Patient/breastpatient01",
"type" : "Patient"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "254837009:363714003=443941007",
"display" : "|Malignant neoplasm of breast (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)|"
}
]
},
"valueInteger" : 1
}
]
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "breastobservation12",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_breastobservation12\"> </a><p><b>Generated Narrative: Observation</b><a name=\"breastobservation12\"> </a><a name=\"hcbreastobservation12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "breastobservation12" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForBreast.html\">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span>, Exam label <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: After 1st Treatment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelExam.html\">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href=\"#Patient_breastpatient01\">See above (Patient/breastpatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code x10^3/μL = 'x10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote></div>"
},
"status" : "final",
"category" : [
{
"text" : "Between 1st and 2nd dose of CT"
},
{
"text" : "Exam label"
}
],
"code" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/LabelExam",
"code" : "1",
"display" : "After 1st Treatment"
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]
},
"subject" : {
"reference" : "Patient/breastpatient01",
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},
"valueInteger" : 2,
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "95218-4",
"display" : "Leukocytes [#/volume] in Stem cell product"
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{
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"coding" : [
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"system" : "http://loinc.org",
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},
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{
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"coding" : [
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"system" : "http://loinc.org",
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},
{
"code" : {
"coding" : [
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"system" : "http://loinc.org",
"code" : "26515-7",
"display" : "Platelets [#/volume] in Blood"
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"valueQuantity" : {
"value" : 287,
"unit" : "per nanolitre",
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"code" : "x10^3/μL"
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},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "41652-9",
"display" : "Glucose [Mass/volume] in Venous blood"
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},
"valueQuantity" : {
"value" : 87,
"unit" : "milligram per decilitre",
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{
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"coding" : [
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},
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"unit" : "milli-international unit per litre",
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},
{
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"coding" : [
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"code" : "20977-5",
"display" : "Urea [Mass/volume] in Blood"
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},
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"value" : 36,
"unit" : "milligram per decilitre",
"system" : "http://unitsofmeasure.org",
"code" : "mg/dL"
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},
{
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"coding" : [
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"system" : "http://loinc.org",
"code" : "38483-4",
"display" : "Creatinine [Mass/volume] in Blood"
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},
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"value" : 0.72,
"unit" : "milligram per decilitre",
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},
{
"code" : {
"coding" : [
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"system" : "http://loinc.org",
"code" : "98981-4",
"display" : "Urate [Mass/volume] in Blood"
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]
},
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"unit" : "milligram per decilitre",
"system" : "http://unitsofmeasure.org",
"code" : "mg/dL"
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},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "75940-7",
"display" : "Potassium [Mass/volume] in Blood"
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]
},
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"unit" : "millimole per litre",
"system" : "http://unitsofmeasure.org",
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{
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"coding" : [
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"system" : "http://loinc.org",
"code" : "2947-0",
"display" : "Sodium [Moles/volume] in Blood"
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},
"valueQuantity" : {
"value" : 142,
"unit" : "millimole per litre",
"system" : "http://unitsofmeasure.org",
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},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "49765-1",
"display" : "Calcium [Mass/volume] in Blood"
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]
},
"valueQuantity" : {
"value" : 9.31,
"unit" : "milligram per decilitre",
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"code" : "mg/dL"
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},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "2093-3",
"display" : "Cholesterol [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity" : {
"value" : 197,
"unit" : "milligram per decilitre",
"system" : "http://unitsofmeasure.org",
"code" : "mg/dL"
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},
{
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"coding" : [
{
"system" : "http://loinc.org",
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},
"valueQuantity" : {
"value" : 59,
"unit" : "milligram per decilitre",
"system" : "http://unitsofmeasure.org",
"code" : "mg/dL"
}
},
{
"code" : {
"coding" : [
{
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}
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