INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
<Bundle xmlns="http://hl7.org/fhir">
<id value="Breast-Cancer-Message-Bundle-Example"/>
<identifier>
<value value="Breast Cancer INCISIVE"/>
</identifier>
<type value="transaction"/>
<timestamp value="2023-07-21T12:29:17.239+02:00"/>
<entry>
<resource>
<MessageHeader>
<id value="breastmessageheader"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MessageHeader_breastmessageheader"> </a><p><b>Generated Narrative: MessageHeader</b><a name="breastmessageheader"> </a><a name="hcbreastmessageheader"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MessageHeader "breastmessageheader" </p></div><p><b>event</b>: Malignant neoplasm of breast (disorder) (Details: http://snomed.org code 254837009 = '254837009', stated as 'Malignant neoplasm of breast (disorder)')</p><h3>Destinations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="https://exemple.com/services?wsdl">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href="#Organization_breastorganization01">See above (Organization/breastorganization01)</a></p><h3>Sources</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="mailto:example@example.en">example@example.en</a></td><td><a href="https://example.en/origin">https://example.en/origin</a></td></tr></table><p><b>focus</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p></div>
</text>
<eventCoding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</eventCoding>
<destination>
<name value="example"/>
<endpoint value="https://exemple.com/services?wsdl"/>
</destination>
<sender>
<reference value="Organization/breastorganization01"/>
<type value="Organization"/>
</sender>
<source>
<name value="example"/>
<contact>
<system value="email"/>
<value value="example@example.en"/>
</contact>
<endpoint value="https://example.en/origin"/>
</source>
<focus>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</focus>
</MessageHeader>
</resource>
<request>
<method value="POST"/>
<url value="MessageHeader"/>
</request>
</entry>
<entry>
<resource>
<Organization>
<id value="breastorganization01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_breastorganization01"> </a><p><b>Generated Narrative: Organization</b><a name="breastorganization01"> </a><a name="hcbreastorganization01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "breastorganization01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-OrganizationINCISIVE.html">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>
</text>
<identifier>
<type>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders"/>
<code value="001"/>
<display value="AUTH"/>
</coding>
</type>
</identifier>
<name value="Aristotle university of Thessaloniki"/>
</Organization>
</resource>
<request>
<method value="POST"/>
<url value="Organization"/>
</request>
</entry>
<entry>
<resource>
<Medication>
<id value="breastmedication01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_breastmedication01"> </a><p><b>Generated Narrative: Medication</b><a name="breastmedication01"> </a><a name="hcbreastmedication01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "breastmedication01" </p></div><p><b>code</b>: Medication therapy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#373873005 "Pharmaceutical / biologic product (product)")</span></p><p><b>status</b>: active</p></div>
</text>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="373873005"/>
<display value="Pharmaceutical / biologic product (product)"/>
</coding>
<text value="Medication therapy"/>
</code>
<status value="active"/>
</Medication>
</resource>
<request>
<method value="POST"/>
<url value="Medication"/>
</request>
</entry>
<entry>
<resource>
<Patient>
<id value="breastpatient01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_breastpatient01"> </a><p><b>Generated Narrative: Patient</b><a name="breastpatient01"> </a><a name="hcbreastpatient01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Patient "breastpatient01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-PatientINCISIVE.html">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-EthnicityOfPatient.html">Ethnicity_of_patient</a>#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>gender</b>: female</p><p><b>managingOrganization</b>: <a href="#Organization_breastorganization01">See above (Organization/breastorganization01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/CurrentState">
<valueCode value="0"/>
</extension>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/Ethnicity">
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/EthnicityOfPatient"/>
<code value="1"/>
<display value="White"/>
</coding>
</valueCodeableConcept>
</extension>
<identifier>
<type>
<text value="Pseudo-anonimized Identifier"/>
</type>
<value value="004-000001"/>
</identifier>
<gender value="female"/>
<managingOrganization>
<reference value="Organization/breastorganization01"/>
</managingOrganization>
</Patient>
</resource>
<request>
<method value="POST"/>
<url value="Patient"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="breastcondition01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_breastcondition01"> </a><p><b>Generated Narrative: Condition</b><a name="breastcondition01"> </a><a name="hcbreastcondition01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "breastcondition01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: N39.8 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#417662000 "History of clinical finding in subject (situation)")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="417662000"/>
<display
value="History of clinical finding in subject (situation)"/>
</coding>
<text value="N39.8"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="breastcondition02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_breastcondition02"> </a><p><b>Generated Narrative: Condition</b><a name="breastcondition02"> </a><a name="hcbreastcondition02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "breastcondition02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Symptoms and signs observed (record artifact) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#63671000122101)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><h3>Evidences</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Nothing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastSymptomsGeneralInfo.html">Symptoms_General_Info_Breast</a>#1)</span></td></tr></table></div>
</text>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="63671000122101"/>
<display value="Symptoms and signs observed (record artifact)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
<evidence>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastSymptomsGeneralInfo"/>
<code value="1"/>
<display value="Nothing"/>
</coding>
</code>
</evidence>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="breastcondition03"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_breastcondition03"> </a><p><b>Generated Narrative: Condition</b><a name="breastcondition03"> </a><a name="hcbreastcondition03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "breastcondition03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#404684003)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Dysuria</p></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
<note>
<text value="Dysuria"/>
</note>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation01"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation01"> </a><a name="hcbreastobservation01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Observation note</p><blockquote><p><b>component</b></p><p><b>code</b>: Number of births at term (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#440425000)</span></p><p><b>value</b>: 2</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Menopause, function (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#161712005)</span></p><p><b>value</b>: Pre <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastPrePostMenopause.html">Pre_post_menopause_Breast</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Carcinoembryonic Ag [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2039-6)</span></p><p><b>value</b>: 11.9 nanogram per milliliter<span style="background: LightGoldenRodYellow"> (Details: UCUM code ng/mL = 'ng/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cancer Ag 15-3 [Units/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#6875-9)</span></p><p><b>value</b>: 37 enzyme unit per millilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/mL = 'U/mL')</span></p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<note>
<text value="Observation note"/>
</note>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="440425000"/>
<display value="Number of births at term (observable entity)"/>
</coding>
</code>
<valueInteger value="2"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="161712005"/>
<display value="Menopause, function (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastPrePostMenopause"/>
<code value="0"/>
<display value="Pre"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=66839005"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=72705000"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2039-6"/>
<display
value="Carcinoembryonic Ag [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="11.9"/>
<unit value="nanogram per milliliter"/>
<system value="http://unitsofmeasure.org"/>
<code value="ng/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="6875-9"/>
<display
value="Cancer Ag 15-3 [Units/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="37"/>
<unit value="enzyme unit per millilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<DiagnosticReport>
<id value="breastdiagnosticReport01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_breastdiagnosticReport01"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name="breastdiagnosticReport01"> </a><a name="hcbreastdiagnosticReport01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport "breastdiagnosticReport01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-DiagnosticReportINCISIVE.html">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>result</b>: <a href="#Observation_breastobservation01">See above (Observation/breastobservation01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis">
<valueAge>
<value value="56"/>
</valueAge>
</extension>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
<result>
<reference value="Observation/breastobservation01"/>
</result>
</DiagnosticReport>
</resource>
<request>
<method value="POST"/>
<url value="DiagnosticReport"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation02"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation02"> </a><a name="hcbreastobservation02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>bodySite</b>: Bone <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastDistantMetastasisLocation.html">Distant_metastasis_location_Breast</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammography.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#71651007 "Mammography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Mammography.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#397137005 "Mammography assessment finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Ultrasound.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#16310003 "Diagnostic ultrasonography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Ultrasound.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#370380004 "Ultrasound scan finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary tumor size (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399734001)</span></p><p><b>value</b>: 4.8 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laterality (attribute) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#272741003)</span></p><p><b>value</b>: Right breast <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastLaterality.html">Breast_laterality</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Radiographic lesion shape finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129732008)</span></p><p><b>value</b>: Oval <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassShape.html">Mass_Shape_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Radiographic lesion margin characteristics (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129737002)</span></p><p><b>value</b>: Angular <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassMargin.html">Mass_Margin_Breast</a>#2)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammography reference location (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129771006)</span></p><p><b>value</b>: Parallel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassOrientation.html">Mass_orientation_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Acoustic feature of mass (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#420415002)</span></p><p><b>value</b>: Anechoic <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassEchoPattern.html">Mass_echo_pattern_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Finding of change compared to previous radiologic examination (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#442301001)</span></p><p><b>value</b>: Shadowing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastPosteriorFeatures.html">Posterior_features_Breast</a>#3)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor calcification (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#409769002)</span></p><p><b>value</b>: In mass <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastCalcificationsBaseline.html">Calcifications_baseline_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Associated finding (attribute) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#246090004)</span></p><p><b>value</b>: Skin thickness <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAssociatedFeatures.html">Associated_Features_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammographic breast composition finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129715009)</span></p><p><b>value</b>: Fatty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastComposition.html">Breast_composition</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammographic architectural distortion of breast (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129792006)</span></p><p><b>value</b>: Minimal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastParenchymalEnhancementLevel.html">Parenchymal_enhancement_level_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor configuration (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371500007)</span></p><p><b>value</b>: Symmetric <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastParenchymalEnhancementSymmetry.html">Parenchymal_enhancement_symmetry_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Qualitative distribution of primary malignant neoplasm (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1163261007)</span></p><p><b>value</b>: Unifocal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastPresenceOfFoci.html">Presence_of_foci_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor staging (tumor staging) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254292007)</span></p><p><b>value</b>: Incomplete need additional imaging evaluation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastBIRADSClassification.html">Breast_BIRADS_classification</a>#BI-RADS 0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor staging (tumor staging) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254292007)</span></p><p><b>value</b>: Negative symmetrical and no masses, architectural distortion, or suspicious calcifications <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastBIRADSClassification.html">Breast_BIRADS_classification</a>#BI-RADS 1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary malignant neoplasm of breast with axillary lymph node invasion (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1082901000112100)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Injury of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#62112002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#78873005)</span></p><p><b>value</b>: T0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastDistantMetastasisLocation"/>
<code value="1"/>
<display value="Bone"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="165331007"/>
<display value="Laboratory procedure performed (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="71651007"/>
<display value="Mammography (procedure)"/>
</coding>
<text value="Mammography.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="397137005"/>
<display value="Mammography assessment finding (finding)"/>
</coding>
<text value="Annotated Mammography.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="16310003"/>
<display value="Diagnostic ultrasonography (procedure)"/>
</coding>
<text value="Ultrasound.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="370380004"/>
<display value="Ultrasound scan finding (finding)"/>
</coding>
<text value="Annotated Ultrasound.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399734001"/>
<display value="Primary tumor size (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="272741003"/>
<display value="Laterality (attribute)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastLaterality"/>
<code value="0"/>
<display value="Right breast"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129732008"/>
<display value="Radiographic lesion shape finding (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassShape"/>
<code value="1"/>
<display value="Oval"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129737002"/>
<display
value="Radiographic lesion margin characteristics (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassMargin"/>
<code value="2"/>
<display value="Angular"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129771006"/>
<display value="Mammography reference location (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassOrientation"/>
<code value="1"/>
<display value="Parallel"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="420415002"/>
<display value="Acoustic feature of mass (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassEchoPattern"/>
<code value="1"/>
<display value="Anechoic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="442301001"/>
<display
value="Finding of change compared to previous radiologic examination (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastPosteriorFeatures"/>
<code value="3"/>
<display value="Shadowing"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="409769002"/>
<display value="Tumor calcification (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastCalcificationsBaseline"/>
<code value="1"/>
<display value="In mass"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="246090004"/>
<display value="Associated finding (attribute)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAssociatedFeatures"/>
<code value="1"/>
<display value="Skin thickness"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129715009"/>
<display
value="Mammographic breast composition finding (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastComposition"/>
<code value="1"/>
<display value="Fatty"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129792006"/>
<display
value="Mammographic architectural distortion of breast (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastParenchymalEnhancementLevel"/>
<code value="1"/>
<display value="Minimal"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371500007"/>
<display value="Tumor configuration (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastParenchymalEnhancementSymmetry"/>
<code value="1"/>
<display value="Symmetric"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1163261007"/>
<display
value="Qualitative distribution of primary malignant neoplasm (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastPresenceOfFoci"/>
<code value="1"/>
<display value="Unifocal"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254292007"/>
<display value="Tumor staging (tumor staging)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastBIRADSClassification"/>
<code value="BI-RADS 0"/>
<display value="Incomplete need additional imaging evaluation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254292007"/>
<display value="Tumor staging (tumor staging)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastBIRADSClassification"/>
<code value="BI-RADS 1"/>
<display
value="Negative symmetrical and no masses, architectural distortion, or suspicious calcifications"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1082901000112100"/>
<display
value="Primary malignant neoplasm of breast with axillary lymph node invasion (disorder)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="62112002"/>
<display value="Injury of breast (disorder)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371497001"/>
<display value="pM category (observable entity)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="78873005"/>
<display value="T category (observable entity)"/>
</coding>
</code>
<valueString value="T0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277206009"/>
<display value="N category (observable entity)"/>
</coding>
</code>
<valueString value="N0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277208005"/>
<display value="M category (observable entity)"/>
</coding>
</code>
<valueString value="M0"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation03"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation03"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation03"> </a><a name="hcbreastobservation03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>bodySite</b>: Nipple and Areola <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastBaselineLocation.html">Baseline_location_Breast</a>#AN)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77477000 "Computed tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000 "Magnetic resonance imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#82918005 "Positron emission tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#252416005 "Histopathology test (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#250537006 "Histopathology finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#363680008 "Radiographic imaging procedure (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastBaselineLocation"/>
<code value="AN"/>
<display value="Nipple and Areola"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="77477000"/>
<display value="Computed tomography (procedure)"/>
</coding>
<text value="CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=77477000"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"/>
</coding>
<text value="Annotated CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="113091000"/>
<display value="Magnetic resonance imaging (procedure)"/>
</coding>
<text value="MRI.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365853002:418775008=113091000"/>
<display
value="|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"/>
</coding>
<text value="Annotated MRI.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="82918005"/>
<display value="Positron emission tomography (procedure)"/>
</coding>
<text value="PET/CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=450436003"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|"/>
</coding>
<text value="Annotated PET/CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="252416005"/>
<display value="Histopathology test (procedure)"/>
</coding>
<text value="Histopathology Image.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="250537006"/>
<display value="Histopathology finding (finding)"/>
</coding>
<text value="Annotated Histopathology Image.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="363680008"/>
<display value="Radiographic imaging procedure (procedure)"/>
</coding>
<text value="Xray.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=168537006"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"/>
</coding>
<text value="Annotated Xray.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure01"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure01"> </a><a name="hcbreastprocedure01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgery <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129125009 "Procedure with explicit context (situation)")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129125009"/>
<display value="Procedure with explicit context (situation)"/>
</coding>
<text value="Surgery"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation04"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation04"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation04"> </a><a name="hcbreastobservation04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>partOf</b>: <a href="#Procedure_breastprocedure01">See above (Procedure/breastprocedure01)</a></p><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label timepoints <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTimepoints.html">Label_Timepoints</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: 2</p><p><b>note</b>: Observation note</p><p><b>bodySite</b>: Bone <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastDistantMetastasisLocation.html">Distant_metastasis_location_Breast</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Mammography.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#71651007 "Mammography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Mammography.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#397137005 "Mammography assessment finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Ultrasound.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#16310003 "Diagnostic ultrasonography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Ultrasound.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#370380004 "Ultrasound scan finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77477000 "Computed tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000 "Magnetic resonance imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#82918005 "Positron emission tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#252416005 "Histopathology test (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#250537006 "Histopathology finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#363680008 "Radiographic imaging procedure (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAnnotatedDicomFiles.html">Annotated_Dicom_files_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Response to treatment (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#182985004)</span></p><p><b>value</b>: CR <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastResponseToTreatment.html">Response_to_treatment_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#78873005)</span></p><p><b>value</b>: T0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor staging (tumor staging) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254292007)</span></p><p><b>value</b>: Incomplete need additional imaging evaluation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastBIRADSClassification.html">Breast_BIRADS_classification</a>#BI-RADS 0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor staging (tumor staging) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254292007)</span></p><p><b>value</b>: Negative symmetrical and no masses, architectural distortion, or suspicious calcifications <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastBIRADSClassification.html">Breast_BIRADS_classification</a>#BI-RADS 1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Length dimension of neoplasm (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#263605001)</span></p><p><b>value</b>: 4.8 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary malignant neoplasm of breast with axillary lymph node invasion (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1082901000112100)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Lesion observable (observable entity)|:|Relative to part of (attribute)|=|Breast structure (body structure)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#364636000:719715003=76752008)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Follow-up status (finding)|:|After (attribute)=|Biopsy (procedure)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#308273005:255234002=86273004)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Follow-up status (finding)|:|After (attribute)|=|Surgical procedure (procedure)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#308273005:255234002=387713003)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor progression (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#419835002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Radiographic lesion shape finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129732008)</span></p><p><b>value</b>: Oval <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassShape.html">Mass_Shape_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Radiographic lesion margin characteristics (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129737002)</span></p><p><b>value</b>: Angular <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassMargin.html">Mass_Margin_Breast</a>#2)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammography reference location (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129771006)</span></p><p><b>value</b>: Parallel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassOrientation.html">Mass_orientation_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Acoustic feature of mass (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#420415002)</span></p><p><b>value</b>: Anechoic <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastMassEchoPattern.html">Mass_echo_pattern_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Finding of change compared to previous radiologic examination (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#442301001)</span></p><p><b>value</b>: Shadowing <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastPosteriorFeatures.html">Posterior_features_Breast</a>#3)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor calcification (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#409769002)</span></p><p><b>value</b>: In mass <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastCalcificationsTimepoints.html">Calcifications_timepoints_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor calcification (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#246090004)</span></p><p><b>value</b>: Skin thickness <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastAssociatedFeatures.html">Associated_Features_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammographic breast composition finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129715009)</span></p><p><b>value</b>: Fatty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastComposition.html">Breast_composition</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Mammographic architectural distortion of breast (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#129792006)</span></p><p><b>value</b>: Minimal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastParenchymalEnhancementLevel.html">Parenchymal_enhancement_level_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor configuration (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371500007)</span></p><p><b>value</b>: Symmetric <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastParenchymalEnhancementSymmetry.html">Parenchymal_enhancement_symmetry_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Qualitative distribution of primary malignant neoplasm (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1163261007)</span></p><p><b>value</b>: Unifocal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastPresenceOfFoci.html">Presence_of_foci_Breast</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Treatment changed (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#445528004)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<partOf>
<reference value="Procedure/breastprocedure01"/>
</partOf>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Label timepoints"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelTimepoints"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueInteger value="2"/>
<note>
<text value="Observation note"/>
</note>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastDistantMetastasisLocation"/>
<code value="1"/>
<display value="Bone"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="71651007"/>
<display value="Mammography (procedure)"/>
</coding>
<text value="Mammography.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="397137005"/>
<display value="Mammography assessment finding (finding)"/>
</coding>
<text value="Annotated Mammography.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="16310003"/>
<display value="Diagnostic ultrasonography (procedure)"/>
</coding>
<text value="Ultrasound.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="370380004"/>
<display value="Ultrasound scan finding (finding)"/>
</coding>
<text value="Annotated Ultrasound.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="77477000"/>
<display value="Computed tomography (procedure)"/>
</coding>
<text value="CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=77477000"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"/>
</coding>
<text value="Annotated CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="113091000"/>
<display value="Magnetic resonance imaging (procedure)"/>
</coding>
<text value="MRI.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365853002:418775008=113091000"/>
<display
value="|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"/>
</coding>
<text value="Annotated MRI.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="82918005"/>
<display value="Positron emission tomography (procedure)"/>
</coding>
<text value="PET/CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=450436003"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|"/>
</coding>
<text value="Annotated PET/CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="252416005"/>
<display value="Histopathology test (procedure)"/>
</coding>
<text value="Histopathology Image.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="250537006"/>
<display value="Histopathology finding (finding)"/>
</coding>
<text value="Annotated Histopathology Image.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="363680008"/>
<display value="Radiographic imaging procedure (procedure)"/>
</coding>
<text value="Xray.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=168537006"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"/>
</coding>
<text value="Annotated Xray.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="165331007"/>
<display value="Laboratory procedure performed (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="182985004"/>
<display value="Response to treatment (situation)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastResponseToTreatment"/>
<code value="1"/>
<display value="CR"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="78873005"/>
<display value="T category (observable entity)"/>
</coding>
</code>
<valueString value="T0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277206009"/>
<display value="N category (observable entity)"/>
</coding>
</code>
<valueString value="N0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277208005"/>
<display value="M category (observable entity)"/>
</coding>
</code>
<valueString value="M0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254292007"/>
<display value="Tumor staging (tumor staging)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastBIRADSClassification"/>
<code value="BI-RADS 0"/>
<display value="Incomplete need additional imaging evaluation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254292007"/>
<display value="Tumor staging (tumor staging)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastBIRADSClassification"/>
<code value="BI-RADS 1"/>
<display
value="Negative symmetrical and no masses, architectural distortion, or suspicious calcifications"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="263605001"/>
<display
value="Length dimension of neoplasm (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1082901000112100"/>
<display
value="Primary malignant neoplasm of breast with axillary lymph node invasion (disorder)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="364636000:719715003=76752008"/>
<display
value="|Lesion observable (observable entity)|:|Relative to part of (attribute)|=|Breast structure (body structure)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371497001"/>
<display value="pM category (observable entity)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="308273005:255234002=86273004"/>
<display
value="|Follow-up status (finding)|:|After (attribute)=|Biopsy (procedure)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="308273005:255234002=387713003"/>
<display
value="|Follow-up status (finding)|:|After (attribute)|=|Surgical procedure (procedure)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="419835002"/>
<display value="Tumor progression (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129732008"/>
<display value="Radiographic lesion shape finding (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassShape"/>
<code value="1"/>
<display value="Oval"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129737002"/>
<display
value="Radiographic lesion margin characteristics (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassMargin"/>
<code value="2"/>
<display value="Angular"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129771006"/>
<display value="Mammography reference location (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassOrientation"/>
<code value="1"/>
<display value="Parallel"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="420415002"/>
<display value="Acoustic feature of mass (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMassEchoPattern"/>
<code value="1"/>
<display value="Anechoic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="442301001"/>
<display
value="Finding of change compared to previous radiologic examination (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastPosteriorFeatures"/>
<code value="3"/>
<display value="Shadowing"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="409769002"/>
<display value="Tumor calcification (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastCalcificationsTimepoints"/>
<code value="1"/>
<display value="In mass"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="246090004"/>
<display value="Tumor calcification (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastAssociatedFeatures"/>
<code value="1"/>
<display value="Skin thickness"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129715009"/>
<display
value="Mammographic breast composition finding (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastComposition"/>
<code value="1"/>
<display value="Fatty"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="129792006"/>
<display
value="Mammographic architectural distortion of breast (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastParenchymalEnhancementLevel"/>
<code value="1"/>
<display value="Minimal"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371500007"/>
<display value="Tumor configuration (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastParenchymalEnhancementSymmetry"/>
<code value="1"/>
<display value="Symmetric"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1163261007"/>
<display
value="Qualitative distribution of primary malignant neoplasm (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastPresenceOfFoci"/>
<code value="1"/>
<display value="Unifocal"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="445528004"/>
<display value="Treatment changed (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="breastcondition04"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_breastcondition04"> </a><p><b>Generated Narrative: Condition</b><a name="breastcondition04"> </a><a name="hcbreastcondition04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "breastcondition04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Symptoms and signs observed (record artifact) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#63671000122101)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><h3>Evidences</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Breast pain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastSymptomsTimepoints.html">Symptoms_Timepoints_Breast</a>#1)</span></td></tr></table></div>
</text>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="63671000122101"/>
<display value="Symptoms and signs observed (record artifact)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
<evidence>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastSymptomsTimepoints"/>
<code value="1"/>
<display value="Breast pain"/>
</coding>
</code>
</evidence>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="breastcondition05"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_breastcondition05"> </a><p><b>Generated Narrative: Condition</b><a name="breastcondition05"> </a><a name="hcbreastcondition05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "breastcondition05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#404684003)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>note</b>: Dysuria</p></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
</subject>
<note>
<text value="Dysuria"/>
</note>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<MedicationAdministration>
<id value="breastmedicationAdministration01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationAdministration_breastmedicationAdministration01"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name="breastmedicationAdministration01"> </a><a name="hcbreastmedicationAdministration01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationAdministration "breastmedicationAdministration01" </p></div><p><b>status</b>: completed</p><p><b>medication</b>: <a href="#Medication_breastmedication01">See above (Medication/breastmedication01)</a></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>effective</b>: 2023-07-21 17:07:54+0000</p><h3>Dosages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Route</b></td><td><b>Dose</b></td><td><b>Rate[x]</b></td></tr><tr><td style="display: none">*</td><td>|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Breast structure (body structure)|, |Units (attribute)|=|Gray (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371892002:704327008=76752008, 246514001=229029004)</span></td><td>40.4</td><td>28 fractions</td></tr></table></div>
</text>
<status value="completed"/>
<medicationReference>
<reference value="Medication/breastmedication01"/>
<type value="Medication"/>
</medicationReference>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<effectiveDateTime value="2023-07-21T17:07:54+00:00"/>
<dosage>
<route>
<coding>
<system value="http://snomed.org"/>
<code
value="371892002:704327008=76752008, 246514001=229029004"/>
<display
value="|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Breast structure (body structure)|, |Units (attribute)|=|Gray (qualifier value)|"/>
</coding>
</route>
<dose>
<value value="40.4"/>
</dose>
<rateQuantity>
<value value="28"/>
<unit value="fractions"/>
</rateQuantity>
</dosage>
</MedicationAdministration>
</resource>
<request>
<method value="POST"/>
<url value="MedicationAdministration"/>
</request>
</entry>
<entry>
<resource>
<MedicationAdministration>
<id value="breastmedicationAdministration02"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationAdministration_breastmedicationAdministration02"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name="breastmedicationAdministration02"> </a><a name="hcbreastmedicationAdministration02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationAdministration "breastmedicationAdministration02" </p></div><p><b>status</b>: completed</p><p><b>category</b>: Boost radiation therapy (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#445232009)</span></p><p><b>medication</b>: <a href="#Medication_breastmedication01">See above (Medication/breastmedication01)</a></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>effective</b>: 2023-07-21 17:07:54+0000</p><h3>Dosages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Route</b></td><td><b>Dose</b></td><td><b>Rate[x]</b></td></tr><tr><td style="display: none">*</td><td>|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Tumor bed (morphologic abnormality)|, |Units (attribute)|=|Gray (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371892002:704327008=1162492000, 246514001=229029004)</span></td><td>50.4</td><td>7 fractions</td></tr></table></div>
</text>
<status value="completed"/>
<category>
<coding>
<system value="http://snomed.org"/>
<code value="445232009"/>
<display value="Boost radiation therapy (procedure)"/>
</coding>
</category>
<medicationReference>
<reference value="Medication/breastmedication01"/>
<type value="Medication"/>
</medicationReference>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<effectiveDateTime value="2023-07-21T17:07:54+00:00"/>
<dosage>
<route>
<coding>
<system value="http://snomed.org"/>
<code
value="371892002:704327008=1162492000, 246514001=229029004"/>
<display
value="|Delivered radiation dose (observable entity)|:|Direct site (attribute)|=|Tumor bed (morphologic abnormality)|, |Units (attribute)|=|Gray (qualifier value)|"/>
</coding>
</route>
<dose>
<value value="50.4"/>
</dose>
<rateQuantity>
<value value="7"/>
<unit value="fractions"/>
</rateQuantity>
</dosage>
</MedicationAdministration>
</resource>
<request>
<method value="POST"/>
<url value="MedicationAdministration"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation05"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation05"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation05"> </a><a name="hcbreastobservation05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>partOf</b>: </p><ul><li><a href="#MedicationAdministration_breastmedicationAdministration01">See above (MedicationAdministration/breastmedicationAdministration01)</a></li><li><a href="#MedicationAdministration_breastmedicationAdministration02">See above (MedicationAdministration/breastmedicationAdministration02)</a></li></ul><p><b>status</b>: final</p><p><b>code</b>: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Neo-adjuvant - intent (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#18629005:363703001=373847000)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: true</p></div>
</text>
<partOf>
<reference
value="MedicationAdministration/breastmedicationAdministration01"/>
</partOf>
<partOf>
<reference
value="MedicationAdministration/breastmedicationAdministration02"/>
</partOf>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="18629005:363703001=373847000"/>
<display
value="|Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Neo-adjuvant - intent (qualifier value)|"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueBoolean value="true"/>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation06"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation06"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation06"> </a><a name="hcbreastobservation06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation06" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>partOf</b>: </p><ul><li><a href="#MedicationAdministration_breastmedicationAdministration01">See above (MedicationAdministration/breastmedicationAdministration01)</a></li><li><a href="#MedicationAdministration_breastmedicationAdministration02">See above (MedicationAdministration/breastmedicationAdministration02)</a></li></ul><p><b>status</b>: final</p><p><b>code</b>: |Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Adjuvant - intent (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#18629005:363703001=373846009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: true</p></div>
</text>
<partOf>
<reference
value="MedicationAdministration/breastmedicationAdministration01"/>
</partOf>
<partOf>
<reference
value="MedicationAdministration/breastmedicationAdministration02"/>
</partOf>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="18629005:363703001=373846009"/>
<display
value="|Administration of drug or medicament (procedure)|:|Has intent (attribute)|=|Adjuvant - intent (qualifier value)|"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueBoolean value="true"/>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation07"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation07"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation07"> </a><a name="hcbreastobservation07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation07" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment-1st FollowUp <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTreatment.html">Label_Treatment</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: Other treatment details</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Performance measure status (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#241000124106)</span></td><td>5</td></tr></table></div>
</text>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Label treatment"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelTreatment"/>
<code value="1"/>
<display value="After 1st Treatment-1st FollowUp"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueString value="Other treatment details"/>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="241000124106"/>
<display value="Performance measure status (finding)"/>
</coding>
</code>
<valueInteger value="5"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation08"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation08"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation08"> </a><a name="hcbreastobservation08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation08" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Procedure on lymph node (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118890000)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: No <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastLymphNodeSurgery.html">Lymph_node_surgery_Breast</a>#0)</span></p></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118890000"/>
<display value="Procedure on lymph node (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastLymphNodeSurgery"/>
<code value="0"/>
<display value="No"/>
</coding>
</valueCodeableConcept>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure02"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure02"> </a><a name="hcbreastprocedure02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>partOf</b>: <a href="#Observation_breastobservation08">See above (Observation/breastobservation08)</a></p><p><b>status</b>: completed</p><p><b>category</b>: Mastectomy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastTypeOfSurgery.html">Type_of_Surgery_Breast</a>#2)</span></p><p><b>code</b>: Surgical procedure (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<partOf>
<reference value="Observation/breastobservation08"/>
</partOf>
<status value="completed"/>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastTypeOfSurgery"/>
<code value="2"/>
<display value="Mastectomy"/>
</coding>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="387713003"/>
<display value="Surgical procedure (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure03"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure03"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure03"> </a><a name="hcbreastprocedure03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Capecitabine <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#367336001:370130000=410656007 "|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="367336001:370130000=410656007"/>
<display
value="|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Capecitabine"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure04"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure04"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure04"> </a><a name="hcbreastprocedure04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Nitrosoureas <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#703423002:370130000=410656007 "|Combined chemotherapy and radiation therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="703423002:370130000=410656007"/>
<display
value="|Combined chemotherapy and radiation therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Nitrosoureas"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure05"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure05"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure05"> </a><a name="hcbreastprocedure05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Tamoxifen <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#897713009:370130000=410656007 "|Antineoplastic chemoimmunotherapy (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="897713009:370130000=410656007"/>
<display
value="|Antineoplastic chemoimmunotherapy (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Tamoxifen"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure06"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure06"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure06"> </a><a name="hcbreastprocedure06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure06" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Tamoxifen <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#385798007:370130000=410656007 "|Radiation therapy care (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="385798007:370130000=410656007"/>
<display
value="|Radiation therapy care (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Tamoxifen"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure07"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure07"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure07"> </a><a name="hcbreastprocedure07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure07" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Tamoxifen <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#169413002:370130000=410656007 "|Hormone therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="169413002:370130000=410656007"/>
<display
value="|Hormone therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Tamoxifen"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure08"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure08"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure08"> </a><a name="hcbreastprocedure08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure08" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Trastuzumab <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#6021000124103:370130000=410656007 "|Targeted medication therapy review (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 3</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="6021000124103:370130000=410656007"/>
<display
value="|Targeted medication therapy review (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Trastuzumab"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="3"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure09"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure09"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure09"> </a><a name="hcbreastprocedure09"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure09" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Pembrolizumab <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#76334006:370130000=410656007 "|Immunotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="76334006:370130000=410656007"/>
<display
value="|Immunotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Pembrolizumab"/>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation09"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation09"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation09"> </a><a name="hcbreastobservation09"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation09" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: HER2 [Presence] in Breast cancer specimen by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#85319-2)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#85337-4)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Progesterone receptor Ag [Presence] in Breast cancer specimen by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#85339-0)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Melan-A and Ki67 Ag [Identifier] in Tissue by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#74489-6)</span></p><p><b>value</b>: 10 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: BRCA1 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#21639-0)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: BRCA1+BRCA2 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#59041-4)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lymphovascular invasion extent in Cancer specimen Qualitative <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#98260-3)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="85319-2"/>
<display
value="HER2 [Presence] in Breast cancer specimen by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="85337-4"/>
<display
value="Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="85339-0"/>
<display
value="Progesterone receptor Ag [Presence] in Breast cancer specimen by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="74489-6"/>
<display
value="Melan-A and Ki67 Ag [Identifier] in Tissue by Immune stain"/>
</coding>
</code>
<valueQuantity>
<value value="10"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="21639-0"/>
<display
value="BRCA1 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="59041-4"/>
<display
value="BRCA1+BRCA2 gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="98260-3"/>
<display
value="Lymphovascular invasion extent in Cancer specimen Qualitative"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation10"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation10"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation10"> </a><a name="hcbreastobservation10"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation10" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Sampling - action (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#257915005)</span></p><p><b>value</b>: Light microscopy</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Staining method (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#127790008)</span></p><p><b>value</b>: Hematoxylin</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Microscopic specimen observation (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#395538009)</span></p><p><b>value</b>: x10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Biopsy finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365855009)</span></p><p><b>value</b>: example</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="257915005"/>
<display value="Sampling - action (qualifier value)"/>
</coding>
</code>
<valueString value="Light microscopy"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="127790008"/>
<display value="Staining method (procedure)"/>
</coding>
</code>
<valueString value="Hematoxylin"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="395538009"/>
<display value="Microscopic specimen observation (finding)"/>
</coding>
</code>
<valueString value="x10"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365855009"/>
<display value="Biopsy finding (finding)"/>
</coding>
</code>
<valueString value="example"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure10"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure10"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure10"> </a><a name="hcbreastprocedure10"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure10" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>statusReason</b>: Biopsy label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelBiopsy.html">Label_Biopsy</a>#1 "After 1st Treatment")</span></p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastTypeOfBiopsy.html">Type_of_Biopsy_Breast</a>#1 "FNAC")</span></p><p><b>code</b>: Biopsy (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#86273004)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 3</p></div>
</text>
<status value="completed"/>
<statusReason>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelBiopsy"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
<text value="Biopsy label"/>
</statusReason>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastTypeOfBiopsy"/>
<code value="1"/>
<display value="FNAC"/>
</coding>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="86273004"/>
<display value="Biopsy (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="3"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="breastprocedure11"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_breastprocedure11"> </a><p><b>Generated Narrative: Procedure</b><a name="breastprocedure11"> </a><a name="hcbreastprocedure11"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "breastprocedure11" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForBreast.html">Procedure for Breast cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgical procedure (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="387713003"/>
<display value="Surgical procedure (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation11"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation11"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation11"> </a><a name="hcbreastobservation11"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation11" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Inflammatory Breast Carcinoma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-BreastCancerType.html">Breast_Cancer_Type</a>#IBC; <a href="CodeSystem-BreastMolecularSubtype.html">Molecular_Subtype_Breast</a>#1 "Luminal A")</span></p><p><b>code</b>: Malignant neoplasm of breast (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>|Malignant neoplasm of breast (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#254837009:363714003=443941007)</span></td><td>1</td></tr></table></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastCancerType"/>
<code value="IBC"/>
<display value="Inflammatory Breast Carcinoma"/>
</coding>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/BreastMolecularSubtype"/>
<code value="1"/>
<display value="Luminal A"/>
</coding>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="254837009:363714003=443941007"/>
<display
value="|Malignant neoplasm of breast (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)|"/>
</coding>
</code>
<valueInteger value="1"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="breastobservation12"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForBreast"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_breastobservation12"> </a><p><b>Generated Narrative: Observation</b><a name="breastobservation12"> </a><a name="hcbreastobservation12"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "breastobservation12" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForBreast.html">Observation for Breast cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Exam label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelExam.html">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_breastpatient01">See above (Patient/breastpatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code x10^3/μL = 'x10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Exam label"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelExam"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
</code>
<subject>
<reference value="Patient/breastpatient01"/>
<type value="Patient"/>
</subject>
<valueInteger value="2"/>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="95218-4"/>
<display value="Leukocytes [#/volume] in Stem cell product"/>
</coding>
</code>
<valueQuantity>
<value value="15.8"/>
<unit value="per microlitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="x10^9/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="718-7"/>
<display value="Hemoglobin [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="16.7"/>
<unit value="gram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="gr/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20570-8"/>
<display value="Hematocrit [Volume Fraction] of Blood"/>
</coding>
</code>
<valueQuantity>
<value value="47.4"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="26515-7"/>
<display value="Platelets [#/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="287"/>
<unit value="per nanolitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="x10^3/μL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="41652-9"/>
<display value="Glucose [Mass/volume] in Venous blood"/>
</coding>
</code>
<valueQuantity>
<value value="87"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20448-7"/>
<display value="Insulin [Units/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="4"/>
<unit value="milli-international unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mlU/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20977-5"/>
<display value="Urea [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="36"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="38483-4"/>
<display value="Creatinine [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="0.72"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="98981-4"/>
<display value="Urate [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="3.5"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="75940-7"/>
<display value="Potassium [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="millimole per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mmol/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2947-0"/>
<display value="Sodium [Moles/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="142"/>
<unit value="millimole per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mmol/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="49765-1"/>
<display value="Calcium [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="9.31"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2093-3"/>
<display value="Cholesterol [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="197"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="3043-7"/>
<display value="Triglyceride [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="59"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2085-9"/>
<display
value="Cholesterol in HDL [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="60"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2089-1"/>
<display
value="Cholesterol in LDL [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="120"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="1920-8"/>
<display
value="Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="19"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="76625-3"/>
<display
value="Alanine aminotransferase [Enzymatic activity/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="33"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2324-2"/>
<display
value="Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="14"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="1783-0"/>
<display
value="Alkaline phosphatase [Enzymatic activity/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="227"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="11053-6"/>
<display
value="Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells"/>
</coding>
</code>
<valueQuantity>
<value value="270"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="3015-5"/>
<display value="Thyrotropin [Units/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="0.73"/>
<unit value="milli-international unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mlU/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2143-6"/>
<display value="Cortisol [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="22"/>
<unit value="gram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="g/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="71426-1"/>
<display
value="C reactive protein [Mass/volume] in Blood by High sensitivity method"/>
</coding>
</code>
<valueQuantity>
<value value="0.5"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="42637-9"/>
<display value="Natriuretic peptide B [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="120"/>
<unit value="picogram per millilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="pg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="17856-6"/>
<display
value="Hemoglobin A1c/Hemoglobin.total in Blood by HPLC"/>
</coding>
</code>
<valueQuantity>
<value value="5.1"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="13986-5"/>
<display
value="Albumin/Protein.total in 24 hour Urine by Electrophoresis"/>
</coding>
</code>
<valueQuantity>
<value value="80"/>
<unit value="milligram per 24 hour"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/24h"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2161-8"/>
<display value="Creatinine [Mass/volume] in Urine"/>
</coding>
</code>
<valueQuantity>
<value value="100"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
</Bundle>
INCISIVE has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952179. However, the content of this website reflects the opinion of its authors and does not in any way represent opinions of the European Union. European Commission is not responsible for any use that may be made of the information the website contains.
https://ec.europa.eu/digital-single-market/en/policies/ehealth