INCISIVE Implementation Guide
0.1.1 - draft

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: Tumor profile result model of Lung cancer to the FHIR Profile map - XML Representation

Draft as of 2024-03-19

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<ConceptMap xmlns="http://hl7.org/fhir">
  <id value="LungTumorProfileResultConceptMap"/>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p>Mapping from <a href="StructureDefinition-LungTumorProfileResultLogicalModel.html">Tumor profile result Lung</a> to <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p><p>DRAFT (not intended for production usage). Published on 2024-03-19 13:26:22+0100 by INCISIVE (INCISIVE: <a href="https://incisive-project.eu/">https://incisive-project.eu/</a>, <a href="mailto:fhir@incisive-project.eu">fhir@incisive-project.eu</a>). </p><div><p>Tumor profile result model of Lung cancer to the FHIR Profile map</p>
</div><br/><p><b>Group 1</b>Mapping from <a href="StructureDefinition-LungTumorProfileResultLogicalModel.html">Tumor profile result Lung</a> to <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p><table class="grid"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td></tr><tr><td>LungTumorProfileResultLogicalModel.tumorProfileResultID (An identifier for the tumor profile result)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.id</td></tr><tr><td>LungTumorProfileResultLogicalModel.patientID (INCISIVE patient)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#equivalent" title="equivalent">is equivalent to</a></td><td>Observation.subject.reference</td></tr><tr><td>LungTumorProfileResultLogicalModel.pdl1 (PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.kras (KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.pik3ca (PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.erbb2 (ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.igf1r (Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.ros1 (Chromosome region 6q22 rearrangements in Tissue by FISH)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.ret (RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.met (MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.her2 (HER2 Ag [Presence] in Tissue by Immune stain)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.egfr (EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueQuantity</td></tr><tr><td>LungTumorProfileResultLogicalModel.alk (ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.braf (BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto" title="relatedto">is related to</a></td><td>Observation.component.valueBoolean</td></tr></table></div>
  </text>
  <url
       value="https://fhir.incisive-project.eu/ConceptMap/LungTumorProfileResultConceptMap"/>
  <version value="0.1.1"/>
  <name value="LungTumorProfileResultConceptMap"/>
  <title
         value="Tumor profile result model of Lung cancer to the FHIR Profile map"/>
  <status value="draft"/>
  <experimental value="true"/>
  <date value="2024-03-19T13:26:22+01:00"/>
  <publisher value="INCISIVE"/>
  <contact>
    <name value="INCISIVE"/>
    <telecom>
      <system value="url"/>
      <value value="https://incisive-project.eu/"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@incisive-project.eu"/>
    </telecom>
  </contact>
  <description
               value="Tumor profile result model of Lung cancer to the FHIR Profile map"/>
  <purpose
           value="It shows how the tumor profile result model of Lung cancer is mapped into the FHIR Profile/structureDefinition"/>
  <sourceUri
             value="https://fhir.incisive-project.eu/StructureDefinition/LungTumorProfileResultLogicalModel"/>
  <targetUri
             value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
  <group>
    <source
            value="https://fhir.incisive-project.eu/StructureDefinition/LungTumorProfileResultLogicalModel"/>
    <target
            value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
    <element>
      <code value="LungTumorProfileResultLogicalModel.tumorProfileResultID"/>
      <display value="An identifier for the tumor profile result"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.id"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.patientID"/>
      <display value="INCISIVE patient"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="equivalent"/>
        </modifierExtension>
        <code value="Observation.subject.reference"/>
        <equivalence value="equivalent"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.pdl1"/>
      <display
               value="PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.kras"/>
      <display
               value="KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.pik3ca"/>
      <display
               value="PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.erbb2"/>
      <display
               value="ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.igf1r"/>
      <display
               value="Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.ros1"/>
      <display
               value="Chromosome region 6q22 rearrangements in Tissue by FISH"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.ret"/>
      <display
               value="RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.met"/>
      <display
               value="MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.her2"/>
      <display value="HER2 Ag [Presence] in Tissue by Immune stain"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.egfr"/>
      <display
               value="EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueQuantity"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.alk"/>
      <display
               value="ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
    <element>
      <code value="LungTumorProfileResultLogicalModel.braf"/>
      <display
               value="BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
      <target>
        <modifierExtension
                           url="http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence">
          <valueCode value="relatedto"/>
        </modifierExtension>
        <code value="Observation.component.valueBoolean"/>
        <equivalence value="relatedto"/>
      </target>
    </element>
  </group>
</ConceptMap>

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