INCISIVE Implementation Guide
0.1.1 - draft

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: Tumor profile result model of Lung cancer to the FHIR Profile map - JSON Representation

Draft as of 2024-03-19

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{
  "resourceType" : "ConceptMap",
  "id" : "LungTumorProfileResultConceptMap",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Mapping from <a href=\"StructureDefinition-LungTumorProfileResultLogicalModel.html\">Tumor profile result Lung</a> to <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p><p>DRAFT (not intended for production usage). Published on 2024-03-19 13:26:22+0100 by INCISIVE (INCISIVE: <a href=\"https://incisive-project.eu/\">https://incisive-project.eu/</a>, <a href=\"mailto:fhir@incisive-project.eu\">fhir@incisive-project.eu</a>). </p><div><p>Tumor profile result model of Lung cancer to the FHIR Profile map</p>\n</div><br/><p><b>Group 1</b>Mapping from <a href=\"StructureDefinition-LungTumorProfileResultLogicalModel.html\">Tumor profile result Lung</a> to <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p><table class=\"grid\"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td></tr><tr><td>LungTumorProfileResultLogicalModel.tumorProfileResultID (An identifier for the tumor profile result)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.id</td></tr><tr><td>LungTumorProfileResultLogicalModel.patientID (INCISIVE patient)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#equivalent\" title=\"equivalent\">is equivalent to</a></td><td>Observation.subject.reference</td></tr><tr><td>LungTumorProfileResultLogicalModel.pdl1 (PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.kras (KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.pik3ca (PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.erbb2 (ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.igf1r (Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.ros1 (Chromosome region 6q22 rearrangements in Tissue by FISH)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.ret (RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.met (MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.her2 (HER2 Ag [Presence] in Tissue by Immune stain)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.egfr (EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueQuantity</td></tr><tr><td>LungTumorProfileResultLogicalModel.alk (ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr><tr><td>LungTumorProfileResultLogicalModel.braf (BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal)</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#relatedto\" title=\"relatedto\">is related to</a></td><td>Observation.component.valueBoolean</td></tr></table></div>"
  },
  "url" : "https://fhir.incisive-project.eu/ConceptMap/LungTumorProfileResultConceptMap",
  "version" : "0.1.1",
  "name" : "LungTumorProfileResultConceptMap",
  "title" : "Tumor profile result model of Lung cancer to the FHIR Profile map",
  "status" : "draft",
  "experimental" : true,
  "date" : "2024-03-19T13:26:22+01:00",
  "publisher" : "INCISIVE",
  "contact" : [
    {
      "name" : "INCISIVE",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://incisive-project.eu/"
        },
        {
          "system" : "email",
          "value" : "fhir@incisive-project.eu"
        }
      ]
    }
  ],
  "description" : "Tumor profile result model of Lung cancer to the FHIR Profile map",
  "purpose" : "It shows how the tumor profile result model of Lung cancer is mapped into the FHIR Profile/structureDefinition",
  "sourceUri" : "https://fhir.incisive-project.eu/StructureDefinition/LungTumorProfileResultLogicalModel",
  "targetUri" : "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung",
  "group" : [
    {
      "source" : "https://fhir.incisive-project.eu/StructureDefinition/LungTumorProfileResultLogicalModel",
      "target" : "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung",
      "element" : [
        {
          "code" : "LungTumorProfileResultLogicalModel.tumorProfileResultID",
          "display" : "An identifier for the tumor profile result",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.id",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.patientID",
          "display" : "INCISIVE patient",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "equivalent"
                }
              ],
              "code" : "Observation.subject.reference",
              "equivalence" : "equivalent"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.pdl1",
          "display" : "PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.kras",
          "display" : "KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.pik3ca",
          "display" : "PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.erbb2",
          "display" : "ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.igf1r",
          "display" : "Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.ros1",
          "display" : "Chromosome region 6q22 rearrangements in Tissue by FISH",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.ret",
          "display" : "RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.met",
          "display" : "MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.her2",
          "display" : "HER2 Ag [Presence] in Tissue by Immune stain",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.egfr",
          "display" : "EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueQuantity",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.alk",
          "display" : "ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        },
        {
          "code" : "LungTumorProfileResultLogicalModel.braf",
          "display" : "BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal",
          "target" : [
            {
              "modifierExtension" : [
                {
                  "url" : "http://hl7.org/fhir/1.0/StructureDefinition/extension-ConceptMap.element.target.equivalence",
                  "valueCode" : "relatedto"
                }
              ],
              "code" : "Observation.component.valueBoolean",
              "equivalence" : "relatedto"
            }
          ]
        }
      ]
    }
  ]
}

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