INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
<Bundle xmlns="http://hl7.org/fhir">
<id value="Lung-Cancer-Message-Bundle-Example"/>
<identifier>
<value value="Lung Cancer INCISIVE"/>
</identifier>
<type value="transaction"/>
<timestamp value="2023-07-24T12:29:17.239+02:00"/>
<entry>
<resource>
<MessageHeader>
<id value="lungmessageheader"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MessageHeader_lungmessageheader"> </a><p><b>Generated Narrative: MessageHeader</b><a name="lungmessageheader"> </a><a name="hclungmessageheader"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MessageHeader "lungmessageheader" </p></div><p><b>event</b>: Primary malignant neoplasm of lung (disorder) (Details: http://snomed.org code 93880001 = '93880001', stated as 'Primary malignant neoplasm of lung (disorder)')</p><h3>Destinations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="https://exemple.com/services?wsdl">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href="#Organization_lungorganization01">See above (Organization/lungorganization01)</a></p><h3>Sources</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="mailto:example@example.en">example@example.en</a></td><td><a href="https://exemple.cat/origin">https://exemple.cat/origin</a></td></tr></table><p><b>focus</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p></div>
</text>
<eventCoding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</eventCoding>
<destination>
<name value="example"/>
<endpoint value="https://exemple.com/services?wsdl"/>
</destination>
<sender>
<reference value="Organization/lungorganization01"/>
<type value="Organization"/>
</sender>
<source>
<name value="example"/>
<contact>
<system value="email"/>
<value value="example@example.en"/>
</contact>
<endpoint value="https://exemple.cat/origin"/>
</source>
<focus>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</focus>
</MessageHeader>
</resource>
<request>
<method value="POST"/>
<url value="MessageHeader"/>
</request>
</entry>
<entry>
<resource>
<Organization>
<id value="lungorganization01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_lungorganization01"> </a><p><b>Generated Narrative: Organization</b><a name="lungorganization01"> </a><a name="hclungorganization01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "lungorganization01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-OrganizationINCISIVE.html">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>
</text>
<identifier>
<type>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders"/>
<code value="001"/>
<display value="AUTH"/>
</coding>
</type>
</identifier>
<name value="Aristotle university of Thessaloniki"/>
</Organization>
</resource>
<request>
<method value="POST"/>
<url value="Organization"/>
</request>
</entry>
<entry>
<resource>
<Medication>
<id value="lungmedication01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_lungmedication01"> </a><p><b>Generated Narrative: Medication</b><a name="lungmedication01"> </a><a name="hclungmedication01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "lungmedication01" </p></div><p><b>code</b>: Medication therapy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#373873005 "Pharmaceutical / biologic product (product)")</span></p><p><b>status</b>: active</p></div>
</text>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="373873005"/>
<display value="Pharmaceutical / biologic product (product)"/>
</coding>
<text value="Medication therapy"/>
</code>
<status value="active"/>
</Medication>
</resource>
<request>
<method value="POST"/>
<url value="Medication"/>
</request>
</entry>
<entry>
<resource>
<Patient>
<id value="lungpatient01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_lungpatient01"> </a><p><b>Generated Narrative: Patient</b><a name="lungpatient01"> </a><a name="hclungpatient01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Patient "lungpatient01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-PatientINCISIVE.html">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-EthnicityOfPatient.html">Ethnicity_of_patient</a>#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>gender</b>: female</p><p><b>managingOrganization</b>: <a href="#Organization_lungorganization01">See above (Organization/lungorganization01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/CurrentState">
<valueCode value="0"/>
</extension>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/Ethnicity">
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/EthnicityOfPatient"/>
<code value="1"/>
<display value="White"/>
</coding>
</valueCodeableConcept>
</extension>
<identifier>
<type>
<text value="Pseudo-anonimized Identifier"/>
</type>
<value value="004-000001"/>
</identifier>
<gender value="female"/>
<managingOrganization>
<reference value="Organization/lungorganization01"/>
</managingOrganization>
</Patient>
</resource>
<request>
<method value="POST"/>
<url value="Patient"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="lungcondition01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_lungcondition01"> </a><p><b>Generated Narrative: Condition</b><a name="lungcondition01"> </a><a name="hclungcondition01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "lungcondition01" </p></div><p><b>code</b>: N39.8 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#417662000 "History of clinical finding in subject (situation)")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="417662000"/>
<display
value="History of clinical finding in subject (situation)"/>
</coding>
<text value="N39.8"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
</subject>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation01"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation01"> </a><a name="hclungobservation01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>note</b>: Observation note</p><blockquote><p><b>component</b></p><p><b>code</b>: Emphysema (morphologic abnormality) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#49158009)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<note>
<text value="Observation note"/>
</note>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="49158009"/>
<display value="Emphysema (morphologic abnormality)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=66839005"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=72705000"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation02"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation02"> </a><a name="hclungobservation02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Smoker (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77176002)</span></p><p><b>value</b>: Are you a smoker? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungSmoker.html">Smoker_Lung</a>#2 "Ex")</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Total time smoked (observable entity)|:|Units (attribute)|=|year (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#228487000:246514001=258707000)</span></p><p><b>value</b>: 10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Cigarette consumption (observable entity)|:|Units (attribute)|=|per day (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#230056004:246514001=259032004)</span></p><p><b>value</b>: 15</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Age at smoking cessation (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1221000175102)</span></p><p><b>value</b>: 50</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="77176002"/>
<display value="Smoker (finding)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungSmoker"/>
<code value="2"/>
<display value="Ex"/>
</coding>
<text value="Are you a smoker?"/>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="228487000:246514001=258707000"/>
<display
value="|Total time smoked (observable entity)|:|Units (attribute)|=|year (qualifier value)|"/>
</coding>
</code>
<valueInteger value="10"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="230056004:246514001=259032004"/>
<display
value="|Cigarette consumption (observable entity)|:|Units (attribute)|=|per day (qualifier value)|"/>
</coding>
</code>
<valueInteger value="15"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1221000175102"/>
<display value="Age at smoking cessation (observable entity)"/>
</coding>
</code>
<valueInteger value="50"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<DiagnosticReport>
<id value="lungdiagnosticReport01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_lungdiagnosticReport01"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name="lungdiagnosticReport01"> </a><a name="hclungdiagnosticReport01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport "lungdiagnosticReport01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-DiagnosticReportINCISIVE.html">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>result</b>: <a href="#Observation_lungobservation01">See above (Observation/lungobservation01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis">
<valueAge>
<value value="56"/>
</valueAge>
</extension>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
</subject>
<result>
<reference value="Observation/lungobservation01"/>
</result>
</DiagnosticReport>
</resource>
<request>
<method value="POST"/>
<url value="DiagnosticReport"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation03"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation03"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation03"> </a><a name="hclungobservation03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>bodySite</b>: Liver <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungDistantMetastasisLocationBaseline.html">Distant_metastasis_location_baseline_Lung</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoptysis (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#66857006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cough (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#49727002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Dyspnea (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#267036007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Weight loss (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#89362005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Performance measure status (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#241000124106)</span></p><p><b>value</b>: 5</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laterality (attribute) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#272741003)</span></p><p><b>value</b>: Right lung <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungLaterality.html">Laterality_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lobe of lung (body structure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#31094006)</span></p><p><b>value</b>: Right upper lobe <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungLobe.html">Lobe_Lung</a>#RUL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary tumor size (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399734001)</span></p><p><b>value</b>: 4.8 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lung volume, function (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#17785005)</span></p><p><b>value</b>: 4500000 cubic millimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mm^3 = 'mm^3')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Consistency (attribute) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#246191002)</span></p><p><b>value</b>: Solid <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungSolidity.html">Solidity_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Central zone necrosis (morphologic abnormality) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#125363000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cavity (morphologic abnormality) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#2483006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor border configuration (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371502004)</span></p><p><b>value</b>: Irregular <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungBorders.html">Borders_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Pleural effusion (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#60046008)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor stage finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#385356007)</span></p><p><b>value</b>: IA3</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#78873005)</span></p><p><b>value</b>: T0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungDistantMetastasisLocationBaseline"/>
<code value="1"/>
<display value="Liver"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="165331007"/>
<display value="Laboratory procedure performed (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="66857006"/>
<display value="Hemoptysis (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="49727002"/>
<display value="Cough (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="267036007"/>
<display value="Dyspnea (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="89362005"/>
<display value="Weight loss (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="241000124106"/>
<display value="Performance measure status (finding)"/>
</coding>
</code>
<valueInteger value="5"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="272741003"/>
<display value="Laterality (attribute)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungLaterality"/>
<code value="0"/>
<display value="Right lung"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="31094006"/>
<display value="Structure of lobe of lung (body structure)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungLobe"/>
<code value="RUL"/>
<display value="Right upper lobe"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399734001"/>
<display value="Primary tumor size (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="17785005"/>
<display value="Lung volume, function (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="4500000"/>
<unit value="cubic millimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mm^3"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="246191002"/>
<display value="Consistency (attribute)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungSolidity"/>
<code value="0"/>
<display value="Solid"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="125363000"/>
<display
value="Central zone necrosis (morphologic abnormality)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="2483006"/>
<display value="Cavity (morphologic abnormality)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371502004"/>
<display
value="Tumor border configuration (observable entity)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungBorders"/>
<code value="0"/>
<display value="Irregular"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="60046008"/>
<display value="Pleural effusion (disorder)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371497001"/>
<display value="pM category (observable entity)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="385356007"/>
<display value="Tumor stage finding (finding)"/>
</coding>
</code>
<valueString value="IA3"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="78873005"/>
<display value="T category (observable entity)"/>
</coding>
</code>
<valueString value="T0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277206009"/>
<display value="N category (observable entity)"/>
</coding>
</code>
<valueString value="N0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277208005"/>
<display value="M category (observable entity)"/>
</coding>
</code>
<valueString value="M0"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation04"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation04"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation04"> </a><a name="hclungobservation04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>bodySite</b>: Same lung <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungNodulesLocation.html">Lung_nodules_location</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lymph node (body structure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#59441001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lymph node station of involved lymph nodes (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#443097008)</span></p><p><b>value</b>: 1</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Length of lymph node in excised specimen (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#364109001)</span></p><p><b>value</b>: 1.3 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Nodule of lung (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#786838002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of tumor nodules (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#405930005)</span></p><p><b>value</b>: 1</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungNodulesLocation"/>
<code value="1"/>
<display value="Same lung"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="59441001"/>
<display value="Structure of lymph node (body structure)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="443097008"/>
<display
value="Lymph node station of involved lymph nodes (observable entity)"/>
</coding>
</code>
<valueString value="1"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="364109001"/>
<display
value="Length of lymph node in excised specimen (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="1.3"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="786838002"/>
<display value="Nodule of lung (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="405930005"/>
<display value="Number of tumor nodules (observable entity)"/>
</coding>
</code>
<valueInteger value="1"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation05"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation05"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation05"> </a><a name="hclungobservation05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77477000 "Computed tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000 "Magnetic resonance imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#82918005 "Positron emission tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#252416005 "Histopathology test (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#250537006 "Histopathology finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#363680008 "Radiographic imaging procedure (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="77477000"/>
<display value="Computed tomography (procedure)"/>
</coding>
<text value="CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=77477000"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"/>
</coding>
<text value="Annotated CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="113091000"/>
<display value="Magnetic resonance imaging (procedure)"/>
</coding>
<text value="MRI.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365853002:418775008=113091000"/>
<display
value="|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"/>
</coding>
<text value="Annotated MRI.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="82918005"/>
<display value="Positron emission tomography (procedure)"/>
</coding>
<text value="PET/CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=450436003"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|"/>
</coding>
<text value="Annotated PET/CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="252416005"/>
<display value="Histopathology test (procedure)"/>
</coding>
<text value="Histopathology Image.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="250537006"/>
<display value="Histopathology finding (finding)"/>
</coding>
<text value="Annotated Histopathology Image.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="363680008"/>
<display value="Radiographic imaging procedure (procedure)"/>
</coding>
<text value="Xray.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=168537006"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"/>
</coding>
<text value="Annotated Xray.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="lungcondition02"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_lungcondition02"> </a><p><b>Generated Narrative: Condition</b><a name="lungcondition02"> </a><a name="hclungcondition02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "lungcondition02" </p></div><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><h3>Evidences</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Other symptoms <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#404684003 "Clinical finding (finding)")</span></td></tr></table></div>
</text>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<evidence>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
<text value="Other symptoms"/>
</code>
</evidence>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation06"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation06"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation06"> </a><a name="hclungobservation06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation06" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label timepoints <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTimepoints.html">Label_Timepoints</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>value</b>: 2</p><p><b>bodySite</b>: Liver <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungDistantMetastasisLocationTimepoints.html">Distant_metastasis_location_timepoints_Lung</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoptysis (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#66857006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cough (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#49727002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Dyspnea (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#267036007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Weight loss (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#89362005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Performance measure status (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#241000124106)</span></p><p><b>value</b>: 5</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary tumor size (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399734001)</span></p><p><b>value</b>: 4.8 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Pleural effusion (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#60046008)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor stage finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#385356007)</span></p><p><b>value</b>: IA3</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Response to treatment (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#182985004)</span></p><p><b>value</b>: CR <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungResponseToTreatment.html">Response_to_treatment_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#78873005)</span></p><p><b>value</b>: T0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote></div>
</text>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Label timepoints"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelTimepoints"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<valueInteger value="2"/>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungDistantMetastasisLocationTimepoints"/>
<code value="1"/>
<display value="Liver"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="371497001"/>
<display value="pM category (observable entity)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="66857006"/>
<display value="Hemoptysis (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="49727002"/>
<display value="Cough (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="267036007"/>
<display value="Dyspnea (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="89362005"/>
<display value="Weight loss (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="241000124106"/>
<display value="Performance measure status (finding)"/>
</coding>
</code>
<valueInteger value="5"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="165331007"/>
<display value="Laboratory procedure performed (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399734001"/>
<display value="Primary tumor size (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="60046008"/>
<display value="Pleural effusion (disorder)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="385356007"/>
<display value="Tumor stage finding (finding)"/>
</coding>
</code>
<valueString value="IA3"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="182985004"/>
<display value="Response to treatment (situation)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungResponseToTreatment"/>
<code value="1"/>
<display value="CR"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="78873005"/>
<display value="T category (observable entity)"/>
</coding>
</code>
<valueString value="T0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277206009"/>
<display value="N category (observable entity)"/>
</coding>
</code>
<valueString value="N0"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="277208005"/>
<display value="M category (observable entity)"/>
</coding>
</code>
<valueString value="M0"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation07"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation07"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation07"> </a><a name="hclungobservation07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation07" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77477000 "Computed tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000 "Magnetic resonance imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#82918005 "Positron emission tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=450436003 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#252416005 "Histopathology test (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#250537006 "Histopathology finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#363680008 "Radiographic imaging procedure (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungAnnotatedDicomFiles.html">Annotated_Dicom_files_Lung</a>#1)</span></p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="77477000"/>
<display value="Computed tomography (procedure)"/>
</coding>
<text value="CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=77477000"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|"/>
</coding>
<text value="Annotated CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="113091000"/>
<display value="Magnetic resonance imaging (procedure)"/>
</coding>
<text value="MRI.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365853002:418775008=113091000"/>
<display
value="|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|"/>
</coding>
<text value="Annotated MRI.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="82918005"/>
<display value="Positron emission tomography (procedure)"/>
</coding>
<text value="PET/CT.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=450436003"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Positron emission tomography with computed tomography (procedure)|"/>
</coding>
<text value="Annotated PET/CT.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="252416005"/>
<display value="Histopathology test (procedure)"/>
</coding>
<text value="Histopathology Image.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="250537006"/>
<display value="Histopathology finding (finding)"/>
</coding>
<text value="Annotated Histopathology Image.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="363680008"/>
<display value="Radiographic imaging procedure (procedure)"/>
</coding>
<text value="Xray.dcm-path"/>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="118247008:418775008=168537006"/>
<display
value="|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|"/>
</coding>
<text value="Annotated Xray.dcm-path"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungAnnotatedDicomFiles"/>
<code value="1"/>
<display value="Positive annotation"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation08"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation08"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation08"> </a><a name="hclungobservation08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation08" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>bodySite</b>: Same lung <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungNodulesLocation.html">Lung_nodules_location</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lymph node (body structure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#59441001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lymph node station of involved lymph nodes (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#443097008)</span></p><p><b>value</b>: 1</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Length of lymph node in excised specimen (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#364109001)</span></p><p><b>value</b>: 1.3 centimetre<span style="background: LightGoldenRodYellow"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Nodule of lung (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#786838002)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<bodySite>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungNodulesLocation"/>
<code value="1"/>
<display value="Same lung"/>
</coding>
</bodySite>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="59441001"/>
<display value="Structure of lymph node (body structure)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="443097008"/>
<display
value="Lymph node station of involved lymph nodes (observable entity)"/>
</coding>
</code>
<valueString value="1"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="364109001"/>
<display
value="Length of lymph node in excised specimen (observable entity)"/>
</coding>
</code>
<valueQuantity>
<value value="1.3"/>
<unit value="centimetre"/>
<system value="http://unitsofmeasure.org"/>
<code value="cm"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="786838002"/>
<display value="Nodule of lung (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="lungcondition03"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_lungcondition03"> </a><p><b>Generated Narrative: Condition</b><a name="lungcondition03"> </a><a name="hclungcondition03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "lungcondition03" </p></div><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><h3>Evidences</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Other symptoms <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#404684003 "Clinical finding (finding)")</span></td></tr></table></div>
</text>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<evidence>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
<text value="Other symptoms"/>
</code>
</evidence>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<MedicationAdministration>
<id value="lungmedicationAdministration01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicationAdministration_lungmedicationAdministration01"> </a><p><b>Generated Narrative: MedicationAdministration</b><a name="lungmedicationAdministration01"> </a><a name="hclungmedicationAdministration01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationAdministration "lungmedicationAdministration01" </p></div><p><b>status</b>: completed</p><p><b>medication</b>: <a href="#Medication_lungmedication01">See above (Medication/lungmedication01)</a></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>effective</b>: 2023-07-24 17:07:54+0000</p><h3>Dosages</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Route</b></td><td><b>Dose</b></td><td><b>Rate[x]</b></td></tr><tr><td style="display: none">*</td><td>Delivered radiation dose (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#371892002)</span></td><td>50.4</td><td>28 fractions</td></tr></table></div>
</text>
<status value="completed"/>
<medicationReference>
<reference value="Medication/lungmedication01"/>
<type value="Medication"/>
</medicationReference>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<effectiveDateTime value="2023-07-24T17:07:54+00:00"/>
<dosage>
<route>
<coding>
<system value="http://snomed.org"/>
<code value="371892002"/>
<display value="Delivered radiation dose (observable entity)"/>
</coding>
</route>
<dose>
<value value="50.4"/>
</dose>
<rateQuantity>
<value value="28"/>
<unit value="fractions"/>
</rateQuantity>
</dosage>
</MedicationAdministration>
</resource>
<request>
<method value="POST"/>
<url value="MedicationAdministration"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation09"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation09"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation09"> </a><a name="hclungobservation09"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation09" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment-1st FollowUp <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTreatment.html">Label_Treatment</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Excision of lymph node (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#58347006)</span></td><td>true</td></tr></table></div>
</text>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Label treatment"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelTreatment"/>
<code value="1"/>
<display value="After 1st Treatment-1st FollowUp"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="58347006"/>
<display value="Excision of lymph node (procedure)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure01"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure01"> </a><a name="hclungprocedure01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>partOf</b>: <a href="#Observation_lungobservation09">See above (Observation/lungobservation09)</a></p><p><b>status</b>: completed</p><p><b>category</b>: Pneumonectomy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003:370130000=410656007 "|Surgical procedure (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>code</b>: Surgical procedure (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p><p><b>bodySite</b>: RUL <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003:363704007=39607008 "|Surgical procedure (procedure)|:|Procedure site (attribute)|=|Lung structure (body structure)|")</span></p></div>
</text>
<partOf>
<reference value="Observation/lungobservation09"/>
</partOf>
<status value="completed"/>
<category>
<coding>
<system value="http://snomed.org"/>
<code value="387713003:370130000=410656007"/>
<display
value="|Surgical procedure (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Pneumonectomy"/>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="387713003"/>
<display value="Surgical procedure (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
<bodySite>
<coding>
<system value="http://snomed.org"/>
<code value="387713003:363704007=39607008"/>
<display
value="|Surgical procedure (procedure)|:|Procedure site (attribute)|=|Lung structure (body structure)|"/>
</coding>
<text value="RUL"/>
</bodySite>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure02"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure02"> </a><a name="hclungprocedure02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Cisplatino <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#367336001:370130000=410656007 "|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="367336001:370130000=410656007"/>
<display
value="|Chemotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Cisplatino"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure03"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure03"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure03"> </a><a name="hclungprocedure03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Crizotinib <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#703423002:370130000=410656007 "|Combined chemotherapy and radiation therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="703423002:370130000=410656007"/>
<display
value="|Combined chemotherapy and radiation therapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Crizotinib"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure04"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure04"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure04"> </a><a name="hclungprocedure04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Crizotinib <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#897713009:370130000=410656007 "|Antineoplastic chemoimmunotherapy (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="897713009:370130000=410656007"/>
<display
value="|Antineoplastic chemoimmunotherapy (regime/therapy)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Crizotinib"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure05"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure05"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure05"> </a><a name="hclungprocedure05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Crizotinib <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#6021000124103:370130000=410656007 "|Targeted medication therapy review (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="6021000124103:370130000=410656007"/>
<display
value="|Targeted medication therapy review (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Crizotinib"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure06"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure06"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure06"> </a><a name="hclungprocedure06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure06" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Alectinib <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#76334006:370130000=410656007 "|Immunotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="76334006:370130000=410656007"/>
<display
value="|Immunotherapy (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)|"/>
</coding>
<text value="Alectinib"/>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure07"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure07"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure07"> </a><a name="hclungprocedure07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure07" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Radiation therapy care (regime/therapy) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#385798007)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="385798007"/>
<display value="Radiation therapy care (regime/therapy)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure08"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure08"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure08"> </a><a name="hclungprocedure08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure08" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>category</b>: Pneumonectomy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003 "Surgical procedure (procedure)")</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<category>
<coding>
<system value="http://snomed.org"/>
<code value="387713003"/>
<display value="Surgical procedure (procedure)"/>
</coding>
<text value="Pneumonectomy"/>
</category>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation10"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation10"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation10"> </a><a name="hclungobservation10"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation10" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#83052-1)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#58483-9)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#100019-9)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#21666-3)</span></p><p><b>value</b>: 10 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: HER2 Ag [Presence] in Tissue by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#18474-7)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#100026-4)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#21734-9)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Chromosome region 6q22 rearrangements in Tissue by FISH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#81747-8)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (loinc#42788-0)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#42783-1)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#63419-6)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#21703-4)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="83052-1"/>
<display
value="PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="58483-9"/>
<display
value="BRAF gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="100019-9"/>
<display
value="ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="21666-3"/>
<display
value="EGFR gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueQuantity>
<value value="10"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="18474-7"/>
<display value="HER2 Ag [Presence] in Tissue by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="100026-4"/>
<display
value="MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="21734-9"/>
<display
value="RET gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="81747-8"/>
<display
value="Chromosome region 6q22 rearrangements in Tissue by FISH"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc"/>
<code value="42788-0"/>
<display
value="Insulin-like growth factor-I receptor Ag [Presence] in Tissue by Immune stain"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="42783-1"/>
<display
value="ERBB2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="63419-6"/>
<display
value="PIK3CA gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="21703-4"/>
<display
value="KRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation11"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation11"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation11"> </a><a name="hclungobservation11"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation11" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Sampling - action (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#257915005)</span></p><p><b>value</b>: Light microscopy</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Staining method (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#127790008)</span></p><p><b>value</b>: Hematoxylin</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Microscopic specimen observation (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#395538009)</span></p><p><b>value</b>: x10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Biopsy finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365855009)</span></p><p><b>value</b>: example</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="257915005"/>
<display value="Sampling - action (qualifier value)"/>
</coding>
</code>
<valueString value="Light microscopy"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="127790008"/>
<display value="Staining method (procedure)"/>
</coding>
</code>
<valueString value="Hematoxylin"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="395538009"/>
<display value="Microscopic specimen observation (finding)"/>
</coding>
</code>
<valueString value="x10"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365855009"/>
<display value="Biopsy finding (finding)"/>
</coding>
</code>
<valueString value="example"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure09"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure09"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure09"> </a><a name="hclungprocedure09"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure09" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>statusReason</b>: Biopsy label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelBiopsy.html">Label_Biopsy</a>#1 "After 1st Treatment")</span></p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: Biopsy (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#86273004)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<statusReason>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelBiopsy"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
<text value="Biopsy label"/>
</statusReason>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="86273004"/>
<display value="Biopsy (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Procedure>
<id value="lungprocedure10"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_lungprocedure10"> </a><p><b>Generated Narrative: Procedure</b><a name="lungprocedure10"> </a><a name="hclungprocedure10"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "lungprocedure10" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForLungAndColorectal.html">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgical procedure (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="387713003"/>
<display value="Surgical procedure (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation12"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation12"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation12"> </a><a name="hclungobservation12"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation12" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Adenocarcinoma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LungCancerType.html">Lung_Cancer_Type</a>#1)</span></p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Primary malignant neoplasm of lung (disorder):|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#93880001:363714003=443941007)</span></td><td>1</td></tr></table></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LungCancerType"/>
<code value="1"/>
<display value="Adenocarcinoma"/>
</coding>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001"/>
<display value="Primary malignant neoplasm of lung (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="93880001:363714003=443941007"/>
<display
value="Primary malignant neoplasm of lung (disorder):|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)|"/>
</coding>
</code>
<valueInteger value="1"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="lungobservation13"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_lungobservation13"> </a><p><b>Generated Narrative: Observation</b><a name="lungobservation13"> </a><a name="hclungobservation13"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "lungobservation13" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForLung.html">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Exam label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelExam.html">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_lungpatient01">See above (Patient/lungpatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code 10^3/μL = '10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<category>
<text value="Exam label"/>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelExam"/>
<code value="1"/>
<display value="After 1st Treatment"/>
</coding>
</code>
<subject>
<reference value="Patient/lungpatient01"/>
<type value="Patient"/>
</subject>
<valueInteger value="2"/>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="95218-4"/>
<display value="Leukocytes [#/volume] in Stem cell product"/>
</coding>
</code>
<valueQuantity>
<value value="15.8"/>
<unit value="per microlitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="x10^9/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="718-7"/>
<display value="Hemoglobin [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="16.7"/>
<unit value="gram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="gr/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20570-8"/>
<display value="Hematocrit [Volume Fraction] of Blood"/>
</coding>
</code>
<valueQuantity>
<value value="47.4"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="26515-7"/>
<display value="Platelets [#/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="287"/>
<unit value="per nanolitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="10^3/μL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="41652-9"/>
<display value="Glucose [Mass/volume] in Venous blood"/>
</coding>
</code>
<valueQuantity>
<value value="87"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20448-7"/>
<display value="Insulin [Units/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="4"/>
<unit value="milli-international unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mlU/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="20977-5"/>
<display value="Urea [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="36"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="38483-4"/>
<display value="Creatinine [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="0.72"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="98981-4"/>
<display value="Urate [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="3.5"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="75940-7"/>
<display value="Potassium [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="4.8"/>
<unit value="millimole per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mmol/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2947-0"/>
<display value="Sodium [Moles/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="142"/>
<unit value="millimole per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mmol/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="49765-1"/>
<display value="Calcium [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="9.31"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2093-3"/>
<display value="Cholesterol [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="197"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="3043-7"/>
<display value="Triglyceride [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="59"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2085-9"/>
<display
value="Cholesterol in HDL [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="60"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2089-1"/>
<display
value="Cholesterol in LDL [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="120"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="1920-8"/>
<display
value="Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="19"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="76625-3"/>
<display
value="Alanine aminotransferase [Enzymatic activity/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="33"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2324-2"/>
<display
value="Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="14"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="1783-0"/>
<display
value="Alkaline phosphatase [Enzymatic activity/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="227"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="11053-6"/>
<display
value="Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells"/>
</coding>
</code>
<valueQuantity>
<value value="270"/>
<unit value="enzyme unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="U/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="3015-5"/>
<display value="Thyrotropin [Units/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="0.73"/>
<unit value="milli-international unit per litre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mlU/L"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2143-6"/>
<display value="Cortisol [Mass/volume] in Serum or Plasma"/>
</coding>
</code>
<valueQuantity>
<value value="22"/>
<unit value="gram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="g/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="71426-1"/>
<display
value="C reactive protein [Mass/volume] in Blood by High sensitivity method"/>
</coding>
</code>
<valueQuantity>
<value value="0.5"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="42637-9"/>
<display value="Natriuretic peptide B [Mass/volume] in Blood"/>
</coding>
</code>
<valueQuantity>
<value value="120"/>
<unit value="picogram per millilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="pg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="17856-6"/>
<display
value="Hemoglobin A1c/Hemoglobin.total in Blood by HPLC"/>
</coding>
</code>
<valueQuantity>
<value value="5.1"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="13986-5"/>
<display
value="Albumin/Protein.total in 24 hour Urine by Electrophoresis"/>
</coding>
</code>
<valueQuantity>
<value value="80"/>
<unit value="milligram per 24 hour"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/24h"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2161-8"/>
<display value="Creatinine [Mass/volume] in Urine"/>
</coding>
</code>
<valueQuantity>
<value value="100"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg/dL"/>
</valueQuantity>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
</Bundle>
INCISIVE has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952179. However, the content of this website reflects the opinion of its authors and does not in any way represent opinions of the European Union. European Commission is not responsible for any use that may be made of the information the website contains.
https://ec.europa.eu/digital-single-market/en/policies/ehealth