INCISIVE Implementation Guide
0.1.1 - draft

INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

: Lung-Cancer-Message-Bundle-Example - JSON Representation

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{
  "resourceType" : "Bundle",
  "id" : "Lung-Cancer-Message-Bundle-Example",
  "identifier" : {
    "value" : "Lung Cancer INCISIVE"
  },
  "type" : "transaction",
  "timestamp" : "2023-07-24T12:29:17.239+02:00",
  "entry" : [
    {
      "resource" : {
        "resourceType" : "MessageHeader",
        "id" : "lungmessageheader",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MessageHeader_lungmessageheader\"> </a><p><b>Generated Narrative: MessageHeader</b><a name=\"lungmessageheader\"> </a><a name=\"hclungmessageheader\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MessageHeader &quot;lungmessageheader&quot; </p></div><p><b>event</b>: Primary malignant neoplasm of lung (disorder) (Details: http://snomed.org code 93880001 = '93880001', stated as 'Primary malignant neoplasm of lung (disorder)')</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"https://exemple.com/services?wsdl\">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_lungorganization01\">See above (Organization/lungorganization01)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"mailto:example@example.en\">example@example.en</a></td><td><a href=\"https://exemple.cat/origin\">https://exemple.cat/origin</a></td></tr></table><p><b>focus</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p></div>"
        },
        "eventCoding" : {
          "system" : "http://snomed.org",
          "code" : "93880001",
          "display" : "Primary malignant neoplasm of lung (disorder)"
        },
        "destination" : [
          {
            "name" : "example",
            "endpoint" : "https://exemple.com/services?wsdl"
          }
        ],
        "sender" : {
          "reference" : "Organization/lungorganization01",
          "type" : "Organization"
        },
        "source" : {
          "name" : "example",
          "contact" : {
            "system" : "email",
            "value" : "example@example.en"
          },
          "endpoint" : "https://exemple.cat/origin"
        },
        "focus" : [
          {
            "reference" : "Patient/lungpatient01",
            "type" : "Patient"
          }
        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "MessageHeader"
      }
    },
    {
      "resource" : {
        "resourceType" : "Organization",
        "id" : "lungorganization01",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_lungorganization01\"> </a><p><b>Generated Narrative: Organization</b><a name=\"lungorganization01\"> </a><a name=\"hclungorganization01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;lungorganization01&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-OrganizationINCISIVE.html\">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>"
        },
        "identifier" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders",
                  "code" : "001",
                  "display" : "AUTH"
                }
              ]
            }
          }
        ],
        "name" : "Aristotle university of Thessaloniki"
      },
      "request" : {
        "method" : "POST",
        "url" : "Organization"
      }
    },
    {
      "resource" : {
        "resourceType" : "Medication",
        "id" : "lungmedication01",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_lungmedication01\"> </a><p><b>Generated Narrative: Medication</b><a name=\"lungmedication01\"> </a><a name=\"hclungmedication01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;lungmedication01&quot; </p></div><p><b>code</b>: Medication therapy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#373873005 &quot;Pharmaceutical / biologic product (product)&quot;)</span></p><p><b>status</b>: active</p></div>"
        },
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "373873005",
              "display" : "Pharmaceutical / biologic product (product)"
            }
          ],
          "text" : "Medication therapy"
        },
        "status" : "active"
      },
      "request" : {
        "method" : "POST",
        "url" : "Medication"
      }
    },
    {
      "resource" : {
        "resourceType" : "Patient",
        "id" : "lungpatient01",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_lungpatient01\"> </a><p><b>Generated Narrative: Patient</b><a name=\"lungpatient01\"> </a><a name=\"hclungpatient01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient &quot;lungpatient01&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PatientINCISIVE.html\">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-EthnicityOfPatient.html\">Ethnicity_of_patient</a>#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>gender</b>: female</p><p><b>managingOrganization</b>: <a href=\"#Organization_lungorganization01\">See above (Organization/lungorganization01)</a></p></div>"
        },
        "extension" : [
          {
            "url" : "https://fhir.incisive-project.eu/StructureDefinition/CurrentState",
            "valueCode" : "0"
          },
          {
            "url" : "https://fhir.incisive-project.eu/StructureDefinition/Ethnicity",
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "https://fhir.incisive-project.eu/CodeSystem/EthnicityOfPatient",
                  "code" : "1",
                  "display" : "White"
                }
              ]
            }
          }
        ],
        "identifier" : [
          {
            "type" : {
              "text" : "Pseudo-anonimized Identifier"
            },
            "value" : "004-000001"
          }
        ],
        "gender" : "female",
        "managingOrganization" : {
          "reference" : "Organization/lungorganization01"
        }
      },
      "request" : {
        "method" : "POST",
        "url" : "Patient"
      }
    },
    {
      "resource" : {
        "resourceType" : "Condition",
        "id" : "lungcondition01",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_lungcondition01\"> </a><p><b>Generated Narrative: Condition</b><a name=\"lungcondition01\"> </a><a name=\"hclungcondition01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition &quot;lungcondition01&quot; </p></div><p><b>code</b>: N39.8 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#417662000 &quot;History of clinical finding in subject (situation)&quot;)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p></div>"
        },
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "417662000",
              "display" : "History of clinical finding in subject (situation)"
            }
          ],
          "text" : "N39.8"
        },
        "subject" : {
          "reference" : "Patient/lungpatient01"
        }
      },
      "request" : {
        "method" : "POST",
        "url" : "Condition"
      }
    },
    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation01",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation01\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation01\"> </a><a name=\"hclungobservation01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation01&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>note</b>: Observation note</p><blockquote><p><b>component</b></p><p><b>code</b>: Emphysema (morphologic abnormality) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#49158009)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote></div>"
        },
        "status" : "final",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
            }
          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
        },
        "note" : [
          {
            "text" : "Observation note"
          }
        ],
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "49158009",
                  "display" : "Emphysema (morphologic abnormality)"
                }
              ]
            },
            "valueBoolean" : true
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "275937001:408732007=66839005",
                  "display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"
                }
              ]
            },
            "valueBoolean" : true
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "275937001:408732007=72705000",
                  "display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"
                }
              ]
            },
            "valueBoolean" : true
          }
        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "Observation"
      }
    },
    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation02",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation02\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation02\"> </a><a name=\"hclungobservation02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation02&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Smoker (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#77176002)</span></p><p><b>value</b>: Are you a smoker? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungSmoker.html\">Smoker_Lung</a>#2 &quot;Ex&quot;)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Total time smoked (observable entity)|:|Units (attribute)|=|year (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#228487000:246514001=258707000)</span></p><p><b>value</b>: 10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Cigarette consumption (observable entity)|:|Units (attribute)|=|per day (qualifier value)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#230056004:246514001=259032004)</span></p><p><b>value</b>: 15</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Age at smoking cessation (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#1221000175102)</span></p><p><b>value</b>: 50</p></blockquote></div>"
        },
        "status" : "final",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
            }
          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "77176002",
                  "display" : "Smoker (finding)"
                }
              ]
            },
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "https://fhir.incisive-project.eu/CodeSystem/LungSmoker",
                  "code" : "2",
                  "display" : "Ex"
                }
              ],
              "text" : "Are you a smoker?"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "228487000:246514001=258707000",
                  "display" : "|Total time smoked (observable entity)|:|Units (attribute)|=|year (qualifier value)|"
                }
              ]
            },
            "valueInteger" : 10
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "230056004:246514001=259032004",
                  "display" : "|Cigarette consumption (observable entity)|:|Units (attribute)|=|per day (qualifier value)|"
                }
              ]
            },
            "valueInteger" : 15
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "1221000175102",
                  "display" : "Age at smoking cessation (observable entity)"
                }
              ]
            },
            "valueInteger" : 50
          }
        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "Observation"
      }
    },
    {
      "resource" : {
        "resourceType" : "DiagnosticReport",
        "id" : "lungdiagnosticReport01",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_lungdiagnosticReport01\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"lungdiagnosticReport01\"> </a><a name=\"hclungdiagnosticReport01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;lungdiagnosticReport01&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DiagnosticReportINCISIVE.html\">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>result</b>: <a href=\"#Observation_lungobservation01\">See above (Observation/lungobservation01)</a></p></div>"
        },
        "extension" : [
          {
            "url" : "https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis",
            "valueAge" : {
              "value" : 56
            }
          }
        ],
        "status" : "final",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
            }
          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01"
        },
        "result" : [
          {
            "reference" : "Observation/lungobservation01"
          }
        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "DiagnosticReport"
      }
    },
    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation03",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation03\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation03\"> </a><a name=\"hclungobservation03\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation03&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>bodySite</b>: Liver <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungDistantMetastasisLocationBaseline.html\">Distant_metastasis_location_baseline_Lung</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoptysis (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#66857006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cough (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#49727002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Dyspnea (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#267036007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Weight loss (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#89362005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Performance measure status (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#241000124106)</span></p><p><b>value</b>: 5</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laterality (attribute) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#272741003)</span></p><p><b>value</b>: Right lung <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungLaterality.html\">Laterality_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lobe of lung (body structure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#31094006)</span></p><p><b>value</b>: Right upper lobe <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungLobe.html\">Lobe_Lung</a>#RUL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary tumor size (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#399734001)</span></p><p><b>value</b>: 4.8 centimetre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lung volume, function (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#17785005)</span></p><p><b>value</b>: 4500000 cubic millimetre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mm^3 = 'mm^3')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Consistency (attribute) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#246191002)</span></p><p><b>value</b>: Solid <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungSolidity.html\">Solidity_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Central zone necrosis (morphologic abnormality) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#125363000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cavity (morphologic abnormality) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#2483006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor border configuration (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#371502004)</span></p><p><b>value</b>: Irregular <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungBorders.html\">Borders_Lung</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Pleural effusion (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#60046008)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor stage finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#385356007)</span></p><p><b>value</b>: IA3</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#78873005)</span></p><p><b>value</b>: T0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote></div>"
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            "valueInteger" : 5
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            "valueCodeableConcept" : {
              "coding" : [
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          },
          {
            "code" : {
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            "valueCodeableConcept" : {
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              ]
            }
          },
          {
            "code" : {
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            "valueQuantity" : {
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              "system" : "http://unitsofmeasure.org",
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          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "246191002",
                  "display" : "Consistency (attribute)"
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              ]
            },
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "https://fhir.incisive-project.eu/CodeSystem/LungSolidity",
                  "code" : "0",
                  "display" : "Solid"
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              ]
            }
          },
          {
            "code" : {
              "coding" : [
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                  "system" : "http://snomed.org",
                  "code" : "125363000",
                  "display" : "Central zone necrosis (morphologic abnormality)"
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              ]
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            "valueBoolean" : true
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          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "2483006",
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              ]
            },
            "valueBoolean" : true
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "371502004",
                  "display" : "Tumor border configuration (observable entity)"
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              ]
            },
            "valueCodeableConcept" : {
              "coding" : [
                {
                  "system" : "https://fhir.incisive-project.eu/CodeSystem/LungBorders",
                  "code" : "0",
                  "display" : "Irregular"
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              ]
            }
          },
          {
            "code" : {
              "coding" : [
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                  "system" : "http://snomed.org",
                  "code" : "60046008",
                  "display" : "Pleural effusion (disorder)"
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              ]
            },
            "valueBoolean" : true
          },
          {
            "code" : {
              "coding" : [
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                  "system" : "http://snomed.org",
                  "code" : "371497001",
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              ]
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            "valueBoolean" : true
          },
          {
            "code" : {
              "coding" : [
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                  "system" : "http://snomed.org",
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            "valueString" : "IA3"
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          {
            "code" : {
              "coding" : [
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                  "display" : "T category (observable entity)"
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              ]
            },
            "valueString" : "T0"
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          {
            "code" : {
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                  "code" : "277206009",
                  "display" : "N category (observable entity)"
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              ]
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            "valueString" : "N0"
          },
          {
            "code" : {
              "coding" : [
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              ]
            },
            "valueString" : "M0"
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        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "Observation"
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    },
    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation04",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation04\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation04\"> </a><a name=\"hclungobservation04\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation04&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>bodySite</b>: Same lung <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungNodulesLocation.html\">Lung_nodules_location</a>#1)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lymph node (body structure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#59441001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lymph node station of involved lymph nodes (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#443097008)</span></p><p><b>value</b>: 1</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Length of lymph node in excised specimen (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#364109001)</span></p><p><b>value</b>: 1.3 centimetre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Nodule of lung (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#786838002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of tumor nodules (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#405930005)</span></p><p><b>value</b>: 1</p></blockquote></div>"
        },
        "status" : "final",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
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        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
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        "bodySite" : {
          "coding" : [
            {
              "system" : "https://fhir.incisive-project.eu/CodeSystem/LungNodulesLocation",
              "code" : "1",
              "display" : "Same lung"
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          ]
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "59441001",
                  "display" : "Structure of lymph node (body structure)"
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            "valueString" : "1"
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            "code" : {
              "coding" : [
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              ]
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            "valueBoolean" : true
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    {
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        "meta" : {
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        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation05\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation05\"> </a><a name=\"hclungobservation05\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation05&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style=\"background: LightGoldenRodYellow; 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        "resourceType" : "Observation",
        "id" : "lungobservation11",
        "meta" : {
          "profile" : [
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        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation11\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation11\"> </a><a name=\"hclungobservation11\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation11&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Sampling - action (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#257915005)</span></p><p><b>value</b>: Light microscopy</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Staining method (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#127790008)</span></p><p><b>value</b>: Hematoxylin</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Microscopic specimen observation (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#395538009)</span></p><p><b>value</b>: x10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Biopsy finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#365855009)</span></p><p><b>value</b>: example</p></blockquote></div>"
        },
        "status" : "final",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
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          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "257915005",
                  "display" : "Sampling - action (qualifier value)"
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            "valueString" : "Light microscopy"
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          {
            "code" : {
              "coding" : [
                {
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                  "code" : "127790008",
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            "valueString" : "Hematoxylin"
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          {
            "code" : {
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                  "code" : "395538009",
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          {
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      "request" : {
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    {
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        "id" : "lungprocedure09",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_lungprocedure09\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"lungprocedure09\"> </a><a name=\"hclungprocedure09\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;lungprocedure09&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForLungAndColorectal.html\">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>statusReason</b>: Biopsy label <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelBiopsy.html\">Label_Biopsy</a>#1 &quot;After 1st Treatment&quot;)</span></p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: Biopsy (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#86273004)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>"
        },
        "status" : "completed",
        "statusReason" : {
          "coding" : [
            {
              "system" : "https://fhir.incisive-project.eu/CodeSystem/LabelBiopsy",
              "code" : "1",
              "display" : "After 1st Treatment"
            }
          ],
          "text" : "Biopsy label"
        },
        "category" : {
          "text" : "Between 1st and 2nd dose of CT"
        },
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "86273004",
              "display" : "Biopsy (procedure)"
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        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
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    {
      "resource" : {
        "resourceType" : "Procedure",
        "id" : "lungprocedure10",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"
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        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_lungprocedure10\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"lungprocedure10\"> </a><a name=\"hclungprocedure10\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;lungprocedure10&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForLungAndColorectal.html\">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgical procedure (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>performed</b>: 2</p></div>"
        },
        "status" : "completed",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "387713003",
              "display" : "Surgical procedure (procedure)"
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        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
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        "performedString" : "2"
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    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation12",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForLung"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation12\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation12\"> </a><a name=\"hclungobservation12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation12&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Adenocarcinoma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LungCancerType.html\">Lung_Cancer_Type</a>#1)</span></p><p><b>code</b>: Primary malignant neoplasm of lung (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Primary malignant neoplasm of lung (disorder):|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#93880001:363714003=443941007)</span></td><td>1</td></tr></table></div>"
        },
        "status" : "final",
        "category" : [
          {
            "coding" : [
              {
                "system" : "https://fhir.incisive-project.eu/CodeSystem/LungCancerType",
                "code" : "1",
                "display" : "Adenocarcinoma"
              }
            ]
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.org",
              "code" : "93880001",
              "display" : "Primary malignant neoplasm of lung (disorder)"
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          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.org",
                  "code" : "93880001:363714003=443941007",
                  "display" : "Primary malignant neoplasm of lung (disorder):|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)|"
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    {
      "resource" : {
        "resourceType" : "Observation",
        "id" : "lungobservation13",
        "meta" : {
          "profile" : [
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        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_lungobservation13\"> </a><p><b>Generated Narrative: Observation</b><a name=\"lungobservation13\"> </a><a name=\"hclungobservation13\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;lungobservation13&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForLung.html\">Observation for Lung cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span>, Exam label <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: After 1st Treatment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelExam.html\">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href=\"#Patient_lungpatient01\">See above (Patient/lungpatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code 10^3/μL = '10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote></div>"
        },
        "status" : "final",
        "category" : [
          {
            "text" : "Between 1st and 2nd dose of CT"
          },
          {
            "text" : "Exam label"
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "https://fhir.incisive-project.eu/CodeSystem/LabelExam",
              "code" : "1",
              "display" : "After 1st Treatment"
            }
          ]
        },
        "subject" : {
          "reference" : "Patient/lungpatient01",
          "type" : "Patient"
        },
        "valueInteger" : 2,
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "95218-4",
                  "display" : "Leukocytes [#/volume] in Stem cell product"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 15.8,
              "unit" : "per microlitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "x10^9/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "718-7",
                  "display" : "Hemoglobin [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 16.7,
              "unit" : "gram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "gr/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "20570-8",
                  "display" : "Hematocrit [Volume Fraction] of Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 47.4,
              "unit" : "% percent",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "26515-7",
                  "display" : "Platelets [#/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 287,
              "unit" : "per nanolitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "10^3/μL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "41652-9",
                  "display" : "Glucose [Mass/volume] in Venous blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 87,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "20448-7",
                  "display" : "Insulin [Units/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 4,
              "unit" : "milli-international unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mlU/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "20977-5",
                  "display" : "Urea [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 36,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "38483-4",
                  "display" : "Creatinine [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 0.72,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "98981-4",
                  "display" : "Urate [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 3.5,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "75940-7",
                  "display" : "Potassium [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 4.8,
              "unit" : "millimole per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mmol/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2947-0",
                  "display" : "Sodium [Moles/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 142,
              "unit" : "millimole per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mmol/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "49765-1",
                  "display" : "Calcium [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 9.31,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2093-3",
                  "display" : "Cholesterol [Mass/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 197,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "3043-7",
                  "display" : "Triglyceride [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 59,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2085-9",
                  "display" : "Cholesterol in HDL [Mass/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 60,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2089-1",
                  "display" : "Cholesterol in LDL [Mass/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 120,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "1920-8",
                  "display" : "Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 19,
              "unit" : "enzyme unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "U/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "76625-3",
                  "display" : "Alanine aminotransferase [Enzymatic activity/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 33,
              "unit" : "enzyme unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "U/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2324-2",
                  "display" : "Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 14,
              "unit" : "enzyme unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "U/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "1783-0",
                  "display" : "Alkaline phosphatase [Enzymatic activity/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 227,
              "unit" : "enzyme unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "U/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "11053-6",
                  "display" : "Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 270,
              "unit" : "enzyme unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "U/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "3015-5",
                  "display" : "Thyrotropin [Units/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 0.73,
              "unit" : "milli-international unit per litre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mlU/L"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2143-6",
                  "display" : "Cortisol [Mass/volume] in Serum or Plasma"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 22,
              "unit" : "gram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "g/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "71426-1",
                  "display" : "C reactive protein [Mass/volume] in Blood by High sensitivity method"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 0.5,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "42637-9",
                  "display" : "Natriuretic peptide B [Mass/volume] in Blood"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 120,
              "unit" : "picogram per millilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "pg/mL"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "17856-6",
                  "display" : "Hemoglobin A1c/Hemoglobin.total in Blood by HPLC"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 5.1,
              "unit" : "% percent",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "13986-5",
                  "display" : "Albumin/Protein.total in 24 hour Urine by Electrophoresis"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 80,
              "unit" : "milligram per 24 hour",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/24h"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://loinc.org",
                  "code" : "2161-8",
                  "display" : "Creatinine [Mass/volume] in Urine"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 100,
              "unit" : "milligram per decilitre",
              "system" : "http://unitsofmeasure.org",
              "code" : "mg/dL"
            }
          }
        ]
      },
      "request" : {
        "method" : "POST",
        "url" : "Observation"
      }
    }
  ]
}

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