INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
{
"resourceType" : "Bundle",
"id" : "Colorectal-Cancer-Message-Bundle-Example",
"identifier" : {
"value" : "Colorectal Cancer INCISIVE"
},
"type" : "transaction",
"timestamp" : "2023-07-25T12:29:17.239+02:00",
"entry" : [
{
"resource" : {
"resourceType" : "MessageHeader",
"id" : "colorectalmessageheader",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MessageHeader_colorectalmessageheader\"> </a><p><b>Generated Narrative: MessageHeader</b><a name=\"colorectalmessageheader\"> </a><a name=\"hccolorectalmessageheader\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MessageHeader "colorectalmessageheader" </p></div><p><b>event</b>: Malignant neoplasm of colon and/or rectum (disorder) (Details: http://snomed.org code 781382000 = '781382000', stated as 'Malignant neoplasm of colon and/or rectum (disorder)')</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"https://exemple.com/services?wsdl\">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_colorectalorganization01\">See above (Organization/colorectalorganization01)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>example</td><td><a href=\"mailto:example@example.com\">example@example.com</a></td><td><a href=\"https://exemple.cat/origin\">https://exemple.cat/origin</a></td></tr></table><p><b>focus</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p></div>"
},
"eventCoding" : {
"system" : "http://snomed.org",
"code" : "781382000",
"display" : "Malignant neoplasm of colon and/or rectum (disorder)"
},
"destination" : [
{
"name" : "example",
"endpoint" : "https://exemple.com/services?wsdl"
}
],
"sender" : {
"reference" : "Organization/colorectalorganization01",
"type" : "Organization"
},
"source" : {
"name" : "example",
"contact" : {
"system" : "email",
"value" : "example@example.com"
},
"endpoint" : "https://exemple.cat/origin"
},
"focus" : [
{
"reference" : "Patient/colorectalpatient01",
"type" : "Patient"
}
]
},
"request" : {
"method" : "POST",
"url" : "MessageHeader"
}
},
{
"resource" : {
"resourceType" : "Organization",
"id" : "colorectalorganization01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_colorectalorganization01\"> </a><p><b>Generated Narrative: Organization</b><a name=\"colorectalorganization01\"> </a><a name=\"hccolorectalorganization01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "colorectalorganization01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-OrganizationINCISIVE.html\">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>"
},
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders",
"code" : "001",
"display" : "AUTH"
}
]
}
}
],
"name" : "Aristotle university of Thessaloniki"
},
"request" : {
"method" : "POST",
"url" : "Organization"
}
},
{
"resource" : {
"resourceType" : "Medication",
"id" : "colorectalmedication01",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_colorectalmedication01\"> </a><p><b>Generated Narrative: Medication</b><a name=\"colorectalmedication01\"> </a><a name=\"hccolorectalmedication01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "colorectalmedication01" </p></div><p><b>code</b>: Medication therapy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#373873005 "Pharmaceutical / biologic product (product)")</span></p><p><b>status</b>: active</p></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "373873005",
"display" : "Pharmaceutical / biologic product (product)"
}
],
"text" : "Medication therapy"
},
"status" : "active"
},
"request" : {
"method" : "POST",
"url" : "Medication"
}
},
{
"resource" : {
"resourceType" : "Patient",
"id" : "colorectalpatient01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_colorectalpatient01\"> </a><p><b>Generated Narrative: Patient</b><a name=\"colorectalpatient01\"> </a><a name=\"hccolorectalpatient01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Patient "colorectalpatient01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PatientINCISIVE.html\">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ([not stated]#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>gender</b>: female</p><p><b>managingOrganization</b>: <a href=\"#Organization_colorectalorganization01\">See above (Organization/colorectalorganization01)</a></p></div>"
},
"extension" : [
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/CurrentState",
"valueCode" : "0"
},
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/Ethnicity",
"valueCodeableConcept" : {
"coding" : [
{
"code" : "1",
"display" : "White"
}
]
}
}
],
"identifier" : [
{
"type" : {
"text" : "Pseudo-anonimized Identifier"
},
"value" : "004-000001"
}
],
"gender" : "female",
"managingOrganization" : {
"reference" : "Organization/colorectalorganization01"
}
},
"request" : {
"method" : "POST",
"url" : "Patient"
}
},
{
"resource" : {
"resourceType" : "Condition",
"id" : "colorectalcondition01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_colorectalcondition01\"> </a><p><b>Generated Narrative: Condition</b><a name=\"colorectalcondition01\"> </a><a name=\"hccolorectalcondition01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Condition "colorectalcondition01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ConditionINCISIVE.html\">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: N39.8 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#417662000 "History of clinical finding in subject (situation)")</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><h3>Evidences</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Hereditary non-polyposis colon cancer syndrome (HNPCC) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ColorectalSyndromes.html\">Syndromes_Colorectal</a>#2)</span></td></tr></table></div>"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "417662000",
"display" : "History of clinical finding in subject (situation)"
}
],
"text" : "N39.8"
},
"subject" : {
"reference" : "Patient/colorectalpatient01"
},
"evidence" : [
{
"code" : [
{
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/ColorectalSyndromes",
"code" : "2",
"display" : "Hereditary non-polyposis colon cancer syndrome (HNPCC)"
}
]
}
]
}
]
},
"request" : {
"method" : "POST",
"url" : "Condition"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "colorectalobservation01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForColorectal"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_colorectalobservation01\"> </a><p><b>Generated Narrative: Observation</b><a name=\"colorectalobservation01\"> </a><a name=\"hccolorectalobservation01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "colorectalobservation01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForColorectal.html\">Observation for Colorectal cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of colon and/or rectum (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#781382000)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>note</b>: Observation note</p><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Carcinoembryonic Ag [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2039-6)</span></p><p><b>value</b>: 11.9 nanogram per millliiter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code ng/mL = 'ng/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cancer Ag 19-9 [Units/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#24108-3)</span></p><p><b>value</b>: 37 enzyme unit per millilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/mL = 'U/mL')</span></p></blockquote></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "781382000",
"display" : "Malignant neoplasm of colon and/or rectum (disorder)"
}
]
},
"subject" : {
"reference" : "Patient/colorectalpatient01",
"type" : "Patient"
},
"note" : [
{
"text" : "Observation note"
}
],
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "275937001:408732007=66839005",
"display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"
}
]
},
"valueBoolean" : true
},
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "275937001:408732007=72705000",
"display" : "|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"
}
]
},
"valueBoolean" : true
},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "2039-6",
"display" : "Carcinoembryonic Ag [Mass/volume] in Serum or Plasma"
}
]
},
"valueQuantity" : {
"value" : 11.9,
"unit" : "nanogram per millliiter",
"system" : "http://unitsofmeasure.org",
"code" : "ng/mL"
}
},
{
"code" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "24108-3",
"display" : "Cancer Ag 19-9 [Units/volume] in Serum or Plasma"
}
]
},
"valueQuantity" : {
"value" : 37,
"unit" : "enzyme unit per millilitre",
"system" : "http://unitsofmeasure.org",
"code" : "U/mL"
}
}
]
},
"request" : {
"method" : "POST",
"url" : "Observation"
}
},
{
"resource" : {
"resourceType" : "DiagnosticReport",
"id" : "colorectaldiagnosticReport01",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_colorectaldiagnosticReport01\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"colorectaldiagnosticReport01\"> </a><a name=\"hccolorectaldiagnosticReport01\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport "colorectaldiagnosticReport01" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DiagnosticReportINCISIVE.html\">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of colon and/or rectum (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#781382000)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>result</b>: <a href=\"#Observation_colorectalobservation01\">See above (Observation/colorectalobservation01)</a></p></div>"
},
"extension" : [
{
"url" : "https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis",
"valueAge" : {
"value" : 56
}
}
],
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "781382000",
"display" : "Malignant neoplasm of colon and/or rectum (disorder)"
}
]
},
"subject" : {
"reference" : "Patient/colorectalpatient01"
},
"result" : [
{
"reference" : "Observation/colorectalobservation01"
}
]
},
"request" : {
"method" : "POST",
"url" : "DiagnosticReport"
}
},
{
"resource" : {
"resourceType" : "Observation",
"id" : "colorectalobservation02",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForColorectal"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_colorectalobservation02\"> </a><p><b>Generated Narrative: Observation</b><a name=\"colorectalobservation02\"> </a><a name=\"hccolorectalobservation02\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "colorectalobservation02" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForColorectal.html\">Observation for Colorectal cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant neoplasm of colon and/or rectum (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#781382000)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>bodySite</b>: Ovary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ColorectalDistantMetastasisLocation.html\">Distant_metastasis_location_Colorectal</a>#3)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Altered bowel function (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#88111009)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Iron deficiency anemia (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#87522002)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Intestinal obstruction (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#81060008)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Weight loss (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#89362005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Laboratory procedure performed (situation) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#165331007)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Primary tumor size (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#399734001)</span></p><p><b>value</b>: 4.8 centimetre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Structure of lymph node (body structure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#59441001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lymph node station of involved lymph nodes (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#443097008)</span></p><p><b>value</b>: 13</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Length of lymph node in excised specimen (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#364109001)</span></p><p><b>value</b>: 9 centimetre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: pM category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#371497001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: T category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#78873005)</span></p><p><b>value</b>: Tis</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: N category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#277206009)</span></p><p><b>value</b>: N0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: M category (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#277208005)</span></p><p><b>value</b>: M0</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Tumor stage finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#385356007)</span></p><p><b>value</b>: IIA</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Malignant tumor of rectum (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#363351006)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Melanocyte stimulating hormone releasing factor (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#43440003)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Venous (large vessel) extramural invasion by tumor present (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#369734008)</span></p><p><b>value</b>: true</p></blockquote></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "781382000",
"display" : "Malignant neoplasm of colon and/or rectum (disorder)"
}
]
},
"subject" : {
"reference" : "Patient/colorectalpatient01",
"type" : "Patient"
},
"bodySite" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/ColorectalDistantMetastasisLocation",
"code" : "3",
"display" : "Ovary"
}
]
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "88111009",
"display" : "Altered bowel function (finding)"
}
]
},
"valueBoolean" : true
},
{
"code" : {
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"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_colorectalprocedure07\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"colorectalprocedure07\"> </a><a name=\"hccolorectalprocedure07\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure "colorectalprocedure07" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForLungAndColorectal.html\">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>statusReason</b>: Biopsy label <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelBiopsy.html\">Label_Biopsy</a>#1 "After 1st Treatment")</span></p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: Biopsy (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#86273004)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>performed</b>: 2</p></div>"
},
"status" : "completed",
"statusReason" : {
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/LabelBiopsy",
"code" : "1",
"display" : "After 1st Treatment"
}
],
"text" : "Biopsy label"
},
"category" : {
"text" : "Between 1st and 2nd dose of CT"
},
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "86273004",
"display" : "Biopsy (procedure)"
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]
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"subject" : {
"reference" : "Patient/colorectalpatient01",
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},
{
"resource" : {
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"id" : "colorectalprocedure08",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ProcedureForLungAndColorectal"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_colorectalprocedure08\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"colorectalprocedure08\"> </a><a name=\"hccolorectalprocedure08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure "colorectalprocedure08" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ProcedureForLungAndColorectal.html\">Procedure for Lung and Colorectal cancer</a></p></div><p><b>status</b>: completed</p><p><b>code</b>: Surgical procedure (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#387713003)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>performed</b>: 2</p></div>"
},
"status" : "completed",
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "387713003",
"display" : "Surgical procedure (procedure)"
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{
"resource" : {
"resourceType" : "Observation",
"id" : "colorectalobservation08",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForColorectal"
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},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_colorectalobservation08\"> </a><p><b>Generated Narrative: Observation</b><a name=\"colorectalobservation08\"> </a><a name=\"hccolorectalobservation08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "colorectalobservation08" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForColorectal.html\">Observation for Colorectal cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Adenocarcinoma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ColorectalCancerType.html\">Colorectal_Cancer_Type</a>#1)</span></p><p><b>code</b>: Malignant neoplasm of colon (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#363406005)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>|Malignant neoplasm of colon (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)| <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (snomed.org#363406005:363714003=443941007)</span></td><td>1</td></tr></table></div>"
},
"status" : "final",
"category" : [
{
"coding" : [
{
"system" : "https://fhir.incisive-project.eu/CodeSystem/ColorectalCancerType",
"code" : "1",
"display" : "Adenocarcinoma"
}
]
}
],
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "363406005",
"display" : "Malignant neoplasm of colon (disorder)"
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},
"subject" : {
"reference" : "Patient/colorectalpatient01",
"type" : "Patient"
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"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.org",
"code" : "363406005:363714003=443941007",
"display" : "|Malignant neoplasm of colon (disorder)|:|Interprets (attribute)|=|Edition of American Joint Commission on Cancer, Cancer Staging Manual used for TNM staging (observable entity)|"
}
]
},
"valueInteger" : 1
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]
},
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"url" : "Observation"
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},
{
"resource" : {
"resourceType" : "Observation",
"id" : "colorectalobservation09",
"meta" : {
"profile" : [
🔗 "https://fhir.incisive-project.eu/StructureDefinition/ObservationForColorectal"
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},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_colorectalobservation09\"> </a><p><b>Generated Narrative: Observation</b><a name=\"colorectalobservation09\"> </a><a name=\"hccolorectalobservation09\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "colorectalobservation09" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationForColorectal.html\">Observation for Colorectal cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span>, Exam label <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>code</b>: After 1st Treatment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-LabelExam.html\">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href=\"#Patient_colorectalpatient01\">See above (Patient/colorectalpatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code x10^3/μL = 'x10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Carcinoembryonic Ag [Mass/volume] in Serum or Plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#2039-6)</span></p><p><b>value</b>: 11.9 nanogram per millliiter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code ng/mL = 'ng/mL')</span></p></blockquote></div>"
},
"status" : "final",
"category" : [
{
"text" : "Between 1st and 2nd dose of CT"
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{
"text" : "Exam label"
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],
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"coding" : [
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},
"valueQuantity" : {
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"unit" : "per nanolitre",
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},
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"coding" : [
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},
"valueQuantity" : {
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"unit" : "milligram per decilitre",
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},
{
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"coding" : [
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},
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"unit" : "milli-international unit per litre",
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"coding" : [
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"system" : "http://loinc.org",
"code" : "20977-5",
"display" : "Urea [Mass/volume] in Blood"
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},
"valueQuantity" : {
"value" : 36,
"unit" : "milligram per decilitre",
"system" : "http://unitsofmeasure.org",
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"coding" : [
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},
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"unit" : "milligram per decilitre",
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