INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide
0.1.1 - draft
INCISIVE Implementation Guide - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
<Bundle xmlns="http://hl7.org/fhir">
<id value="Prostate-Cancer-Message-Bundle-Example"/>
<identifier>
<value value="Prostate Cancer INCISIVE"/>
</identifier>
<type value="transaction"/>
<timestamp value="2023-07-24T12:29:17.239+02:00"/>
<entry>
<resource>
<MessageHeader>
<id value="prostatemessageheader"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MessageHeader_prostatemessageheader"> </a><p><b>Generated Narrative: MessageHeader</b><a name="prostatemessageheader"> </a><a name="hcprostatemessageheader"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MessageHeader "prostatemessageheader" </p></div><p><b>event</b>: Malignant tumor of prostate (disorder) (Details: http://snomed.org code 399068003 = '399068003', stated as 'Malignant tumor of prostate (disorder)')</p><h3>Destinations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="https://exemple.com/services?wsdl">https://exemple.com/services?wsdl</a></td></tr></table><p><b>sender</b>: <a href="#Organization_prostateorganization01">See above (Organization/prostateorganization01)</a></p><h3>Sources</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Contact</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>example</td><td><a href="mailto:example@example.en">example@example.en</a></td><td><a href="https://example.en/origin">https://example.en/origin</a></td></tr></table><p><b>focus</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p></div>
</text>
<eventCoding>
<system value="http://snomed.org"/>
<code value="399068003"/>
<display value="Malignant tumor of prostate (disorder)"/>
</eventCoding>
<destination>
<name value="example"/>
<endpoint value="https://exemple.com/services?wsdl"/>
</destination>
<sender>
<reference value="Organization/prostateorganization01"/>
<type value="Organization"/>
</sender>
<source>
<name value="example"/>
<contact>
<system value="email"/>
<value value="example@example.en"/>
</contact>
<endpoint value="https://example.en/origin"/>
</source>
<focus>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</focus>
</MessageHeader>
</resource>
<request>
<method value="POST"/>
<url value="MessageHeader"/>
</request>
</entry>
<entry>
<resource>
<Organization>
<id value="prostateorganization01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/OrganizationINCISIVE"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_prostateorganization01"> </a><p><b>Generated Narrative: Organization</b><a name="prostateorganization01"> </a><a name="hcprostateorganization01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "prostateorganization01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-OrganizationINCISIVE.html">Organization for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>identifier</b>: AUTH/?ngen-9?</p><p><b>name</b>: Aristotle university of Thessaloniki</p></div>
</text>
<identifier>
<type>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/INCISIVEDataProviders"/>
<code value="001"/>
<display value="AUTH"/>
</coding>
</type>
</identifier>
<name value="Aristotle university of Thessaloniki"/>
</Organization>
</resource>
<request>
<method value="POST"/>
<url value="Organization"/>
</request>
</entry>
<entry>
<resource>
<Medication>
<id value="prostatemedication01"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_prostatemedication01"> </a><p><b>Generated Narrative: Medication</b><a name="prostatemedication01"> </a><a name="hcprostatemedication01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "prostatemedication01" </p></div><p><b>code</b>: Medication therapy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#373873005 "Pharmaceutical / biologic product (product)")</span></p><p><b>status</b>: active</p></div>
</text>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="373873005"/>
<display value="Pharmaceutical / biologic product (product)"/>
</coding>
<text value="Medication therapy"/>
</code>
<status value="active"/>
</Medication>
</resource>
<request>
<method value="POST"/>
<url value="Medication"/>
</request>
</entry>
<entry>
<resource>
<Patient>
<id value="prostatepatient01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/PatientINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_prostatepatient01"> </a><p><b>Generated Narrative: Patient</b><a name="prostatepatient01"> </a><a name="hcprostatepatient01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Patient "prostatepatient01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-PatientINCISIVE.html">Patient for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>CurrentState</b>: 0</p><p><b>Ethnicity</b>: White <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-EthnicityOfPatient.html">Ethnicity_of_patient</a>#1)</span></p><p><b>identifier</b>: Pseudo-anonimized Identifier/004-000001</p><p><b>managingOrganization</b>: <a href="#Organization_prostateorganization01">See above (Organization/prostateorganization01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/CurrentState">
<valueCode value="0"/>
</extension>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/Ethnicity">
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/EthnicityOfPatient"/>
<code value="1"/>
<display value="White"/>
</coding>
</valueCodeableConcept>
</extension>
<identifier>
<type>
<text value="Pseudo-anonimized Identifier"/>
</type>
<value value="004-000001"/>
</identifier>
<managingOrganization>
<reference value="Organization/prostateorganization01"/>
</managingOrganization>
</Patient>
</resource>
<request>
<method value="POST"/>
<url value="Patient"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="prostatecondition01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_prostatecondition01"> </a><p><b>Generated Narrative: Condition</b><a name="prostatecondition01"> </a><a name="hcprostatecondition01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "prostatecondition01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: MG30.10 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#417662000 "History of clinical finding in subject (situation)")</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><h3>Evidences</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Difficulty starting urination <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateSymptomsGeneralInfo.html">Symptoms_General_Info_Prostate</a>#1)</span></td></tr></table></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="417662000"/>
<display
value="History of clinical finding in subject (situation)"/>
</coding>
<text value="MG30.10"/>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
</subject>
<evidence>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstateSymptomsGeneralInfo"/>
<code value="1"/>
<display value="Difficulty starting urination"/>
</coding>
</code>
</evidence>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Condition>
<id value="prostatecondition02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ConditionForBreastColorectalProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_prostatecondition02"> </a><p><b>Generated Narrative: Condition</b><a name="prostatecondition02"> </a><a name="hcprostatecondition02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Condition "prostatecondition02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ConditionINCISIVE.html">Condition for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>code</b>: Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#404684003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>note</b>: Dysuria</p></div>
</text>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
</subject>
<note>
<text value="Dysuria"/>
</note>
</Condition>
</resource>
<request>
<method value="POST"/>
<url value="Condition"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="prostateobservation01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation01"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation01"> </a><a name="hcprostateobservation01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Family history of prostate cancer (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#414205003)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=66839005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#275937001:408732007=72705000)</span></p><p><b>value</b>: true</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399068003"/>
<display value="Malignant tumor of prostate (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="414205003"/>
<display value="Family history of prostate cancer (situation)"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=66839005"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Father (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="275937001:408732007=72705000"/>
<display
value="|Family history of cancer (situation)|:|Subject relationship context (attribute)|=|Mother (person)|"/>
</coding>
</code>
<valueBoolean value="true"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<DiagnosticReport>
<id value="prostatediagnosticReport01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/DiagnosticReportINCISIVE"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_prostatediagnosticReport01"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name="prostatediagnosticReport01"> </a><a name="hcprostatediagnosticReport01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport "prostatediagnosticReport01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-DiagnosticReportINCISIVE.html">DiagnosticReport for Breast, Colorectal, Lung and Prostate cancer</a></p></div><p><b>AgeAtDiagnosis</b>: 56</p><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>result</b>: <a href="#Observation_prostateobservation01">See above (Observation/prostateobservation01)</a></p></div>
</text>
<extension
url="https://fhir.incisive-project.eu/StructureDefinition/AgeAtDiagnosis">
<valueAge>
<value value="56"/>
</valueAge>
</extension>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399068003"/>
<display value="Malignant tumor of prostate (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
</subject>
<result>
<reference value="Observation/prostateobservation01"/>
</result>
</DiagnosticReport>
</resource>
<request>
<method value="POST"/>
<url value="DiagnosticReport"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="prostateobservation02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation02"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation02"> </a><a name="hcprostateobservation02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>bodySite</b>: pZp apex <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateLocalizationOfPIRADS.html">Localization_of_PIRADS_Prostate</a>#3)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#77477000 "Computed tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#82918005 "Positron emission tomography (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated PET/CT.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=77477000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Computed tomography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000 "Magnetic resonance imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated MRI.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365853002:418775008=113091000 "|Imaging finding (finding)|:|Finding method (attribute)|=|Magnetic resonance imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Magnetic resonance imaging (procedure)|:|Property (attribute)|=|Type (property) (qualifier value)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#113091000:370130000=410656007)</span></p><p><b>value</b>: Prior biopsy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateMRITypeBaseline.html">MRI_type_baseline_Prostate</a>#0)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bone Scintigraphy Scan.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#228084000 "Whole body bone imaging (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Bone Scintigraphy Scan.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=228084000 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Whole body bone imaging (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#252416005 "Histopathology test (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Histopathology Image.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#250537006 "Histopathology finding (finding)")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#363680008 "Radiographic imaging procedure (procedure)")</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Annotated Xray.dcm-path <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#118247008:418775008=168537006 "|Radiologic finding (finding)|:|Finding method (attribute)|=|Plain radiography (procedure)|")</span></p><p><b>value</b>: Positive annotation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateAnnotatedDicomFiles.html">Annotated_Dicom_files_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Prostate Adenoma Volume by derived from height, width and length (US) <span style="background: LightGoldenRodYellow; 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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation03"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation03"> </a><a name="hcprostateobservation03"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation03" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>value</b>: 2</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Prostate specific Ag [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2857-1)</span></td><td>4.26 nanogram per millliiter<span style="background: LightGoldenRodYellow"> (Details: UCUM code ng/mL = 'ng/mL')</span></td></tr></table></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation04"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation04"> </a><a name="hcprostateobservation04"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation04" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>value</b>: 3</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Prostate specific Ag [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2857-1)</span></td><td>3.5 nanogram per millliiter<span style="background: LightGoldenRodYellow"> (Details: UCUM code ng/mL = 'ng/mL')</span></td></tr></table></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation05"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation05"> </a><a name="hcprostateobservation05"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation05" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>value</b>: 4</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Prostate specific Ag [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2857-1)</span></td><td>4.1 nanogram per millliiter<span style="background: LightGoldenRodYellow"> (Details: UCUM code ng/mL = 'ng/mL')</span></td></tr></table></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation08"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation08"> </a><a name="hcprostateobservation08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation08" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label timepoints <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTimepoints.html">Label_Timepoints</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: |Malignant tumor of prostate (disorder)|:|Clinical course (attribute)|=|Relapsing course (qualifier value)| <span style="background: LightGoldenRodYellow; 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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation09"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation09"> </a><a name="hcprostateobservation09"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation09" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Label treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment-1st FollowUp <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelTreatment.html">Label_Treatment</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Dissection of lymph node (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#11971000224104)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Response to treatment (situation) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#182985004)</span></p><p><b>value</b>: CR <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateResponseToTreatment.html">Response_to_treatment_Prostate</a>#1)</span></p></blockquote></div>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="182985004"/>
<display value="Response to treatment (situation)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstateResponseToTreatment"/>
<code value="1"/>
<display value="CR"/>
</coding>
</valueCodeableConcept>
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</Observation>
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<request>
<method value="POST"/>
<url value="Observation"/>
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</entry>
<entry>
<resource>
<Procedure>
<id value="prostateprocedure01"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_prostateprocedure01"> </a><p><b>Generated Narrative: Procedure</b><a name="prostateprocedure01"> </a><a name="hcprostateprocedure01"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "prostateprocedure01" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForProstate.html">Procedure for Prostate cancer</a></p></div><p><b>status</b>: completed</p><p><b>category</b>: EBRT = External Beam Radiotherapy <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateTypeOfTherapy.html">Type_of_Therapy_Prostate</a>#0)</span></p><p><b>code</b>: Active surveillance <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateTreatment.html">Treatment_Prostate</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>performed</b>: 2</p></div>
</text>
<status value="completed"/>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstateTypeOfTherapy"/>
<code value="0"/>
<display value="EBRT = External Beam Radiotherapy"/>
</coding>
</category>
<code>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstateTreatment"/>
<code value="1"/>
<display value="Active surveillance"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</subject>
<performedString value="2"/>
</Procedure>
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<request>
<method value="POST"/>
<url value="Procedure"/>
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</entry>
<entry>
<resource>
<Procedure>
<id value="prostateprocedure02"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ProcedureForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Procedure_prostateprocedure02"> </a><p><b>Generated Narrative: Procedure</b><a name="prostateprocedure02"> </a><a name="hcprostateprocedure02"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "prostateprocedure02" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ProcedureForProstate.html">Procedure for Prostate cancer</a></p></div><p><b>status</b>: completed</p><p><b>statusReason</b>: Biopsy label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelBiopsy.html">Label_Biopsy</a>#2 "After 1st Treatment")</span></p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstateTypeOfBiopsy.html">Type_of_Biopsy_Prostate</a>#1 "Randomized biopsy")</span></p><p><b>code</b>: Biopsy (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#86273004)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>performed</b>: 3</p></div>
</text>
<status value="completed"/>
<statusReason>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/LabelBiopsy"/>
<code value="2"/>
<display value="After 1st Treatment"/>
</coding>
<text value="Biopsy label"/>
</statusReason>
<category>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstateTypeOfBiopsy"/>
<code value="1"/>
<display value="Randomized biopsy"/>
</coding>
<text value="Between 1st and 2nd dose of CT"/>
</category>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="86273004"/>
<display value="Biopsy (procedure)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</subject>
<performedString value="3"/>
</Procedure>
</resource>
<request>
<method value="POST"/>
<url value="Procedure"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="prostateobservation10"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation10"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation10"> </a><a name="hcprostateobservation10"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation10" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>partOf</b>: <a href="#Procedure_prostateprocedure02">See above (Procedure/prostateprocedure02)</a></p><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Gleason score (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#372278000)</span></p><p><b>value</b>: 7</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Histologic grade of urothelial carcinoma by World Health Organization and International Society of Urological Pathology technique (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#396659000)</span></p><p><b>value</b>: 4</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Ratio of number of prostatic tissue cores positive for carcinoma to total number of cores obtained by needle biopsy (observable entity)|:|Relative to (attribute)|=|Structure of right lateral lobe of prostate (body structure)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#372280006:704325000=251597001)</span></p><p><b>value</b>: 95 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: |Ratio of number of prostatic tissue cores positive for carcinoma to total number of cores obtained by needle biopsy (observable entity)|:|Relative to (attribute)|=|Structure of left lateral lobe of prostate (body structure)| <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#372280006:704325000=251695000)</span></p><p><b>value</b>: 60 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Non-infiltrating intraductal carcinoma (morphologic abnormality) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#86616005)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cribriform neoplasm pattern (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#443987001)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: American Joint Committee on Cancer pT3b (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1229861009)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: American Joint Committee on Cancer pT3 (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1229859000)</span></p><p><b>value</b>: true</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gleason score (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#372278000)</span></p><p><b>value</b>: 6</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: American Joint Committee on Cancer pathological T category allowable value (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1222589003)</span></p><p><b>value</b>: pT1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstatePTHistologyMutations.html">PT_histology_mutations_Prostate</a>#1)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: American Joint Committee on Cancer pathological N category allowable value (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#1222590007)</span></p><p><b>value</b>: N1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ProstatePNHistologyMutations.html">PN_histology_mutations_Prostate</a>#1)</span></p></blockquote></div>
</text>
<partOf>
<reference value="Procedure/prostateprocedure02"/>
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<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399068003"/>
<display value="Malignant tumor of prostate (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="372278000"/>
<display value="Gleason score (observable entity)"/>
</coding>
</code>
<valueInteger value="7"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="396659000"/>
<display
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</coding>
</code>
<valueInteger value="4"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="372280006:704325000=251597001"/>
<display
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</coding>
</code>
<valueQuantity>
<value value="95"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="372280006:704325000=251695000"/>
<display
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</coding>
</code>
<valueQuantity>
<value value="60"/>
<unit value="% percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="86616005"/>
<display
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</code>
<valueBoolean value="true"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="443987001"/>
<display value="Cribriform neoplasm pattern (finding)"/>
</coding>
</code>
<valueBoolean value="true"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1229861009"/>
<display
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</coding>
</code>
<valueBoolean value="true"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1229859000"/>
<display
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</coding>
</code>
<valueBoolean value="true"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="372278000"/>
<display value="Gleason score (observable entity)"/>
</coding>
</code>
<valueInteger value="6"/>
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<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1222589003"/>
<display
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</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstatePTHistologyMutations"/>
<code value="1"/>
<display value="pT1"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="1222590007"/>
<display
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</coding>
</code>
<valueCodeableConcept>
<coding>
<system
value="https://fhir.incisive-project.eu/CodeSystem/ProstatePNHistologyMutations"/>
<code value="1"/>
<display value="N1"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="prostateobservation11"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation11"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation11"> </a><a name="hcprostateobservation11"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation11" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Malignant tumor of prostate (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#399068003)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Sampling - action (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#257915005)</span></p><p><b>value</b>: Light microscopy</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Staining method (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#127790008)</span></p><p><b>value</b>: Hematoxylin</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Microscopic specimen observation (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#395538009)</span></p><p><b>value</b>: x10</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Biopsy finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (snomed.org#365855009)</span></p><p><b>value</b>: example</p></blockquote></div>
</text>
<status value="final"/>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="399068003"/>
<display value="Malignant tumor of prostate (disorder)"/>
</coding>
</code>
<subject>
<reference value="Patient/prostatepatient01"/>
<type value="Patient"/>
</subject>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="257915005"/>
<display value="Sampling - action (qualifier value)"/>
</coding>
</code>
<valueString value="Light microscopy"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="127790008"/>
<display value="Staining method (procedure)"/>
</coding>
</code>
<valueString value="Hematoxylin"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="395538009"/>
<display value="Microscopic specimen observation (finding)"/>
</coding>
</code>
<valueString value="x10"/>
</component>
<component>
<code>
<coding>
<system value="http://snomed.org"/>
<code value="365855009"/>
<display value="Biopsy finding (finding)"/>
</coding>
</code>
<valueString value="example"/>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<resource>
<Observation>
<id value="prostateobservation12"/>
<meta>
<profile
value="https://fhir.incisive-project.eu/StructureDefinition/ObservationForProstate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_prostateobservation12"> </a><p><b>Generated Narrative: Observation</b><a name="prostateobservation12"> </a><a name="hcprostateobservation12"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "prostateobservation12" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-ObservationForProstate.html">Observation for Prostate cancer</a></p></div><p><b>status</b>: final</p><p><b>category</b>: Between 1st and 2nd dose of CT <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Exam label <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>code</b>: After 1st Treatment <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-LabelExam.html">Label_Exam</a>#1)</span></p><p><b>subject</b>: <a href="#Patient_prostatepatient01">See above (Patient/prostatepatient01)</a></p><p><b>value</b>: 2</p><blockquote><p><b>component</b></p><p><b>code</b>: Leukocytes [#/volume] in Stem cell product <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#95218-4)</span></p><p><b>value</b>: 15.8 per microlitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code x10^9/L = 'x10^9/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#718-7)</span></p><p><b>value</b>: 16.7 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code gr/dL = 'gr/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20570-8)</span></p><p><b>value</b>: 47.4 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Platelets [#/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#26515-7)</span></p><p><b>value</b>: 287 per nanolitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code x10^3/μL = 'x10^3/μL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glucose [Mass/volume] in Venous blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#41652-9)</span></p><p><b>value</b>: 87 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Insulin [Units/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20448-7)</span></p><p><b>value</b>: 4 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urea [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#20977-5)</span></p><p><b>value</b>: 36 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#38483-4)</span></p><p><b>value</b>: 0.72 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Urate [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#98981-4)</span></p><p><b>value</b>: 3.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Potassium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#75940-7)</span></p><p><b>value</b>: 4.8 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Sodium [Moles/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2947-0)</span></p><p><b>value</b>: 142 millimole per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mmol/L = 'mmol/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Calcium [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#49765-1)</span></p><p><b>value</b>: 9.31 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2093-3)</span></p><p><b>value</b>: 197 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Triglyceride [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3043-7)</span></p><p><b>value</b>: 59 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in HDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2085-9)</span></p><p><b>value</b>: 60 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cholesterol in LDL [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2089-1)</span></p><p><b>value</b>: 120 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1920-8)</span></p><p><b>value</b>: 19 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alanine aminotransferase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#76625-3)</span></p><p><b>value</b>: 33 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2324-2)</span></p><p><b>value</b>: 14 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alkaline phosphatase [Enzymatic activity/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#1783-0)</span></p><p><b>value</b>: 227 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#11053-6)</span></p><p><b>value</b>: 270 enzyme unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code U/L = 'U/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Thyrotropin [Units/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#3015-5)</span></p><p><b>value</b>: 0.73 milli-international unit per litre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mlU/L = 'mlU/L')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Cortisol [Mass/volume] in Serum or Plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2143-6)</span></p><p><b>value</b>: 22 gram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code g/dL = 'g/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: C reactive protein [Mass/volume] in Blood by High sensitivity method <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#71426-1)</span></p><p><b>value</b>: 0.5 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Natriuretic peptide B [Mass/volume] in Blood <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#42637-9)</span></p><p><b>value</b>: 120 picogram per millilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code pg/mL = 'pg/mL')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Hemoglobin A1c/Hemoglobin.total in Blood by HPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#17856-6)</span></p><p><b>value</b>: 5.1 % percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Albumin/Protein.total in 24 hour Urine by Electrophoresis <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#13986-5)</span></p><p><b>value</b>: 80 milligram per 24 hour<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/24h = 'mg/24h')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Creatinine [Mass/volume] in Urine <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#2161-8)</span></p><p><b>value</b>: 100 milligram per decilitre<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/dL = 'mg/dL')</span></p></blockquote></div>
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<coding>
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<component>
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<coding>
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<system value="http://unitsofmeasure.org"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
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<code>
<coding>
<system value="http://loinc.org"/>
<code value="26515-7"/>
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<code>
<coding>
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<code>
<coding>
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<valueQuantity>
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<unit value="millimole per litre"/>
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<coding>
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<coding>
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<valueQuantity>
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<code>
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<valueQuantity>
<value value="22"/>
<unit value="gram per decilitre"/>
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<component>
<code>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
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<valueQuantity>
<value value="120"/>
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<system value="http://unitsofmeasure.org"/>
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<coding>
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<valueQuantity>
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<code>
<coding>
<system value="http://loinc.org"/>
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<valueQuantity>
<value value="80"/>
<unit value="milligram per 24 hour"/>
<system value="http://unitsofmeasure.org"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="2161-8"/>
<display value="Creatinine [Mass/volume] in Urine"/>
</coding>
</code>
<valueQuantity>
<value value="100"/>
<unit value="milligram per decilitre"/>
<system value="http://unitsofmeasure.org"/>
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